The England star will return from a groin injury and feature in a backline that will also include Ryan Lamb, Mark Foster and Freddie Burns.
Gloucester have already recorded two victories from their opening two games and another against the Tigers would be a considerable achievement.
There are also places for Henry Trinder and Charlie Sharples, while coach Mark Cornwell includes hooker Scott Lawson, Apo Satala and Dan Williams in his forward pack.
The game is included in the season ticket package and all other tickets cost £5 for adults and £1 for children. Gates will open at 6pm and supporters are advised Gate Two (next to the club shop) will be the only way into the ground.
There will be un-reserved seating in the C&G Grandstand and the Shed will also be open.
GLOUCESTER A (v Leicester, tonight, 7.45pm): Balshaw; Sharples, Trinder, Burns, Foster; Lamb, Lewis; Thomas, Lawson, Knight, Wright, Williams, Satala, Thompson, Pretorious. Reps: Duncan, Meadows, Gilbert, Hooper, Pasqualin, Roberts, Norton.
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