GLOUCESTER have been dealt two major blows ahead of tonight's Guinness Premiership match against Bath at the Rec.
Both wingers - James Simpson-Daniel and Lesley Vainikolo - have been ruled out of the match and are replaced by James Bailey and Leon Lloyd.
Although he has trained this week, Simpson-Daniel has been struck down with a serious case of the flu. Vainikolo, who is the Premiership's leading scorer with seven, is flying home to New Zealand immediately to deal with a serious family problem.
"James reported this morning that he was really not very well at all and last night we were informed of a serious family problem in New Zealand that Lesley needed to attend urgently," said head coach Dean Ryan.
"Naturally, our thoughts are with him, we will give him as much time as he needs and support him on his return. Until that happens, we will be making no further comment."
Bailey has started three Premiership matches this season - against Leicester, Sale and London Irish.
Lloyd has scored five tries this season and has made eight appearances in all competitions. His place on the bench is now taken by Mark Foster, who has appeared in three EDF Energy Cup matches this season.
As Gloucester prepare for their 39th game of the season, against Bordeaux-Begles at Sixways on Sunday, David Humphreys told the local media that this week has been all about getting the players mentally and physically ready after a tough game against Connacht last Sunday.
Speaking to GRTV after the 40-32 victory over Connacht on Sunday, skipper Billy Twelvetrees explained that Gloucester had had to learn to be patient and cut out the errors to earn the win and progress to next weekend's final play-off against Bordeaux-Begles.
Jonny May's superb late score capped a thrilling 40-32 European play-off win over Connacht on Sunday. The winger spoke afterwards of his team's character and spirit as he looked ahead to one more week of rugby.
Speaking to GRTV this afternoon, Director of Rugby David Humphreys hailed the 'never say die' attitude of the team, after despite not being at their best, fighting back to take a 40-32 win after extra time over Connacht.
Jonny May continues on the wing on Sunday as Connacht come to town, and the England wing explains to the local media this week that he is delighted with his form and is looking forward to taking on Pat Lam's men.
Premiership Rugby have this morning confirmed the order of fixtures for the 2015/16 season, and Gloucester Rugby will start their campaign at Kingston Park, taking on Newcastle Falcons on Friday 16 October, 19:45.