GLOUCESTER have been dealt two major blows ahead of tonight's Guinness Premiership match against Bath at the Rec.
Both wingers - James Simpson-Daniel and Lesley Vainikolo - have been ruled out of the match and are replaced by James Bailey and Leon Lloyd.
Although he has trained this week, Simpson-Daniel has been struck down with a serious case of the flu. Vainikolo, who is the Premiership's leading scorer with seven, is flying home to New Zealand immediately to deal with a serious family problem.
"James reported this morning that he was really not very well at all and last night we were informed of a serious family problem in New Zealand that Lesley needed to attend urgently," said head coach Dean Ryan.
"Naturally, our thoughts are with him, we will give him as much time as he needs and support him on his return. Until that happens, we will be making no further comment."
Bailey has started three Premiership matches this season - against Leicester, Sale and London Irish.
Lloyd has scored five tries this season and has made eight appearances in all competitions. His place on the bench is now taken by Mark Foster, who has appeared in three EDF Energy Cup matches this season.
Gloucester travel to Oyonnax for the second round of the European Rugby Challenge Cup on Saturday evening, and Director of Rugby David Humphreys is expecting a big test from the French side, feeling that their league position doesn't reflect their recent performances.
Speaking exclusively to Gloucester Rugby TV, Matt Kvesic explained that his decision to extend his contract at Kingsholm was a simple one and that he was hugely excited for the future in Cherry and White.
Speaking after the 55-0 win over CA Brive, Jonny May told GRTV that he's delighted that the team's hard work is starting to pay dividends but was equally happy for his friend and team mate, Charlie Sharples, on what was a big night for his fellow winger.
Speaking to the local media this week, David Humphreys insisted that Gloucester are looking forward to kicking off the new European Rugby Challenge Cup against Brive on Thursday evening, although an unfamiliar opponent and a five day turnaround will pose a challenge.