GLOUCESTER have been dealt two major blows ahead of tonight's Guinness Premiership match against Bath at the Rec.
Both wingers - James Simpson-Daniel and Lesley Vainikolo - have been ruled out of the match and are replaced by James Bailey and Leon Lloyd.
Although he has trained this week, Simpson-Daniel has been struck down with a serious case of the flu. Vainikolo, who is the Premiership's leading scorer with seven, is flying home to New Zealand immediately to deal with a serious family problem.
"James reported this morning that he was really not very well at all and last night we were informed of a serious family problem in New Zealand that Lesley needed to attend urgently," said head coach Dean Ryan.
"Naturally, our thoughts are with him, we will give him as much time as he needs and support him on his return. Until that happens, we will be making no further comment."
Bailey has started three Premiership matches this season - against Leicester, Sale and London Irish.
Lloyd has scored five tries this season and has made eight appearances in all competitions. His place on the bench is now taken by Mark Foster, who has appeared in three EDF Energy Cup matches this season.
Speaking to the local media this week, David Humphreys insisted that Gloucester are looking forward to kicking off the new European Rugby Challenge Cup against Brive on Thursday evening, although an unfamiliar opponent and a five day turnaround will pose a challenge.
Director of Rugby David Humphreys felt that his Gloucester side put themselves in a position to put Saracens under real pressure at Allianz Park on Saturday, praising his team's commitment and defence, while admitting that a lack of accuracy hit their chances in the second half.
Speaking to the local media at Allianz Park, Tom Savage was disappointed after the defeat at Saracens, but claimed Gloucester did plenty of good things and could've taken more than a losing bonus point.
In case you missed it, there was plenty of activity on the official Gloucester Rugby website following the 55-0 European Rugby Challenge Cup win over CA Brive, including a number of post match video interviews.
The Cherry and Whites ran in six tries in beating CA Brive 55-0 on Thursday night. An emphatic second half performance saw the hosts run in five tries to get the European campaign off to a flying start.
Gloucester took their time to go through the gears in Thursday's European Rugby Challenge Cup opener but turned on the style in the second half to emerge 55-0 winners and get their campaign off to a winning start.