GLOUCESTER will welcome back a raft of internationals on Sunday when they make the trip to the Memorial Stadium to face Bristol (3pm).
England trio Lesley Vainikolo, Iain Balshaw and Luke Narraway will be joined by Scotland's Chris Paterson, Italy's Marco Bortolami and Carlos Nieto and Gareth Delve of Wales in a much-changed line-up named by head coach Dean Ryan.
The changes will see a significant shift in Ryan's starting line-up following their 20-13 defeat to Leicester last weekend.
Paterson will return at stand-off to replace Willie Walker and will make his fourth start of the season at number 10. Ryan Lamb is ruled out with a shoulder injury. He will partner Gareth Cooper at half-back, who makes his first Premiership start since Gloucester's 20-13 victory away to Newcastle before Christmas.
The centre partnership of Anthony Allen and Jack Adams remains the same as the one that faced Leicester, while James Simpson-Daniel will be partnered by Vainikolo - who will make his first start since the victory over Ulster in January - and full-back Iain Balshaw, who comes in for James Bailey in the back three.
Up front, there are also considerable changes. Nick Wood is the only remaining member of the front row that start against Leicester as Carlos Nieto returns at tight-head and is joined at hooker by Jeremy Paul, who will make his first Guinness Premiership start.
At lock, Marco Bortolami returns from the fractured eye socket sustained against Ulster and will partner Will James. Peter Buxton, who has featured in 16 games this season, moves to the bench.
Narraway, who has won his first two England caps against Wales and Italy, comes in at number six in place of Alasdair Strokosch, Andy Hazell retains the number seven shirt and Gareth Delve returns at number eight.
"Although we lost against Leicester last weekend we saw a clear image of what we want to be as a side," Ryan said. "We can take a lot of positives from that performance and obviously this week the group has returned to something like full strength so we want to see a continuation of that process.
"Losing a game like last weekend is not a huge concern simply because of what we got out of it and how we can progress it long-term. We are beginning a period of some crucial matches and that continues on Sunday against Bristol.
"We know they are an outstanding side at the nuts and bolts of the game and when that functions they are capable of taking a team apart - you only have to look at what happened to Stade Francais in the Heineken Cup to appreciate their threat.
"It is our job to get our game right and if that unfolds in the right way I am confident we have the ability to match anybody. These games are special - they are special for the supporters and special for the players and it is something we are looking forward to."
On the bench, scrum-half Rory Lawson will be joined by utility back Willie Walker and wing Mark Foster.
The forwards are made up of hooker Andy Titterrell as Olivier Azam is given a rest, prop Alasdair Dickinson, Buxton and Strokosch.
GLOUCESTER (v Bristol, Sunday, 3pm): Iain Balshaw; James Simpson-Daniel, Jack Adams, Anthony Allen, Lesley Vainikolo; Chris Paterson, Gareth Cooper; Nick Wood, Jeremy Paul, Carlos Nieto, Marco Bortolami (capt), Will James, Luke Narraway, Andy Hazell, Gareth Delve. Reps: Andy Titterrell, Alasdair Dickinson, Peter Buxton, Alasdair Strokosch, Rory Lawson, Willie Walker, Mark Foster.
Tom Savage delivered a Man of the Match performance against Exeter Chiefs on his birthday on Saturday evening. He spoke to GRTV after the game about the importance of the European Rugby Challenge Cup win.
Speaking to the local media this week, John Afoa described the hard work that the Cherry and White have been putting in and that he is fighting fit ready for Saturday's European Rugby Challenge Cup semi final clash with Exeter Chiefs.
Gloucester Rugby face Exeter Chiefs this Saturday in the European Rugby Challenge Cup semi-final, and Charlie Sharples, who starts at full back is relishing the challenge of the big Kingsholm occasion.
Gloucester meet the Exeter Chiefs for the fourth time in competitive action this weekend, this time in the semi-final of the European Rugby Challenge Cup. Director of Rugby David Humphreys told the local media this week that this is the sort of game that Gloucester want to be involved in on a regular basis and that he and his team are looking forward to it.
Following the 29-26 loss to Harlequins, club captain Billy Twelvetrees spoke of his disappointment that the Cherry and Whites were unable to cash in on the home side's indiscipline and lose a lead on Saturday afternoon.
Number eight Gareth Evans admitted to a collective feeling of frustration as Gloucester lost narrowly at Harlequins on Saturday, but insisted that there are plenty of positives to draw upon ahead of next Saturday's European Rugby Challenge Cup semi-final at home to Exeter.
The Gloucester Rugby Ticket office can advise that the club's initial allocation of tickets for the European Rugby Challenge Cup Final has sold out. However, the club has secured an additional allocation of tickets from EPCR which will go on sale on Monday.
Following Saturday evening's exciting European Rugby Challenge Cup semi-final victory over Exeter Chiefs, the Ticket Office at Kingsholm will be open on Sunday from 11am to 3pm for Club Members to purchase tickets for the Final.
Gloucester Rugby qualified for their first European final since 2006 as they defeated the in-form Exeter Chiefs by 30 points to 19 in a thrilling semi-final at Kingsholm on Saturday evening. The club photographer caught the best of the action.
Recent meetings between these two teams have often been thrillers, and this was no exception. It went down to the final few minutes, but Gloucester produced the goods when it mattered to qualify for the European Rugby Challenge Cup Final, beating Exeter 30-19.