GLOUCESTER will welcome back a raft of internationals on Sunday when they make the trip to the Memorial Stadium to face Bristol (3pm).
England trio Lesley Vainikolo, Iain Balshaw and Luke Narraway will be joined by Scotland's Chris Paterson, Italy's Marco Bortolami and Carlos Nieto and Gareth Delve of Wales in a much-changed line-up named by head coach Dean Ryan.
The changes will see a significant shift in Ryan's starting line-up following their 20-13 defeat to Leicester last weekend.
Paterson will return at stand-off to replace Willie Walker and will make his fourth start of the season at number 10. Ryan Lamb is ruled out with a shoulder injury. He will partner Gareth Cooper at half-back, who makes his first Premiership start since Gloucester's 20-13 victory away to Newcastle before Christmas.
The centre partnership of Anthony Allen and Jack Adams remains the same as the one that faced Leicester, while James Simpson-Daniel will be partnered by Vainikolo - who will make his first start since the victory over Ulster in January - and full-back Iain Balshaw, who comes in for James Bailey in the back three.
Up front, there are also considerable changes. Nick Wood is the only remaining member of the front row that start against Leicester as Carlos Nieto returns at tight-head and is joined at hooker by Jeremy Paul, who will make his first Guinness Premiership start.
At lock, Marco Bortolami returns from the fractured eye socket sustained against Ulster and will partner Will James. Peter Buxton, who has featured in 16 games this season, moves to the bench.
Narraway, who has won his first two England caps against Wales and Italy, comes in at number six in place of Alasdair Strokosch, Andy Hazell retains the number seven shirt and Gareth Delve returns at number eight.
"Although we lost against Leicester last weekend we saw a clear image of what we want to be as a side," Ryan said. "We can take a lot of positives from that performance and obviously this week the group has returned to something like full strength so we want to see a continuation of that process.
"Losing a game like last weekend is not a huge concern simply because of what we got out of it and how we can progress it long-term. We are beginning a period of some crucial matches and that continues on Sunday against Bristol.
"We know they are an outstanding side at the nuts and bolts of the game and when that functions they are capable of taking a team apart - you only have to look at what happened to Stade Francais in the Heineken Cup to appreciate their threat.
"It is our job to get our game right and if that unfolds in the right way I am confident we have the ability to match anybody. These games are special - they are special for the supporters and special for the players and it is something we are looking forward to."
On the bench, scrum-half Rory Lawson will be joined by utility back Willie Walker and wing Mark Foster.
The forwards are made up of hooker Andy Titterrell as Olivier Azam is given a rest, prop Alasdair Dickinson, Buxton and Strokosch.
GLOUCESTER (v Bristol, Sunday, 3pm): Iain Balshaw; James Simpson-Daniel, Jack Adams, Anthony Allen, Lesley Vainikolo; Chris Paterson, Gareth Cooper; Nick Wood, Jeremy Paul, Carlos Nieto, Marco Bortolami (capt), Will James, Luke Narraway, Andy Hazell, Gareth Delve. Reps: Andy Titterrell, Alasdair Dickinson, Peter Buxton, Alasdair Strokosch, Rory Lawson, Willie Walker, Mark Foster.
Gloucester Rugby will take on Wasps on Sunday in their first ever visit in the Aviva Premiership to the Ricoh Arena. Speaking to the local media today, Director of Rugby David Humphreys previewed the game as well as giving an update on the injured Henry Trinder.
Following the 48-10 Aviva Premiership win over London Welsh on Saturday, Dan Murphy praised his team mates for battling right up to the very last minute in difficult conditions and maintaining the momentum that the team have built in 2015.
Henry Purdy scored two memorable tries against London Welsh at Kingsholm on Saturday, and attributed the first one to hard work on the training ground before describing how much he's enjoying playing his rugby alongside friends like Callum Braley.
Gloucester face London Welsh for the third time this season when they meet at Kingsholm in the Aviva Premiership on Saturday (kick off 3pm), but Director of Rugby David Humphreys insists his team are prepared for a tough game against the Exiles.
Billy Burns was a late call up to the Gloucester team that lost narrowly to the Leicester Tigers at Welford Road on Friday evening and, speaking to GRTV post match, was full of praise for his team-mates but admitted that defeat was tough to take.
A number of the Gloucester Rugby squad this week benefitted from an initiative organised by Circle 2 Success (C2S) and the Rugby Players Association (RPA) to help players develop their business planning skills.