He will continue his rehabilitation for six weeks following consultation with specialist Andy Williams, the same doctor used by number eight James Forrester in the recovery process of his own knee injury last season.
Following an MRI scan last week, it was revealed that Bortolami does not require surgery and will continue with his rehabilitation accordingly.
"Although the injury is not as serious as an ACL or MCL it needed immediate attention in order to clear it up so I can resume with Gloucester for pre-season," Bortolami told www.gloucesterrugby.co.uk.
"The injury was the main reason I could not finish the Guinness Premiership semi-final against Leicester and I am obviously extremely disappointed to miss out on selection to Italy's squad to face World Champions South Africa. I will continue my rehabilitation in Italy for the next few weeks before returning to Gloucester."
Bortolami will join both James Simpson-Daniel and Nick Wood in undergoing recovery this summer.
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