Gloucester Rugby players Dan Williams (number 8) and Luke Narraway (number 6) are keeping their fingers crossed and hoping a local resident wins the bumper jackpot.
The players took a moment away from training at Kingsholm to encourage their supporters to 'try' their luck in the draw which, if won by a single ticket holder, would be the biggest lottery prize ever paid out in the UK.
The South West saw the biggest ever Lottery win this year when Nigel Page and Justine Laycock from Cirencester banked and incredible £56m in February.
EuroMillions offers a greater range of prizes than any other National Lottery draw, with 12 prize levels in total. In the UK it also includes the Millionaire Raffle which guarantees to create a millionaire on these shores every week.
It costs £2 to play and tickets are available from over 28,000 National Lottery retailers across the UK, online at www.national-lottery.co.uk and via mobile phones using the Play by Text service.