The side also boasts international experience in the second row where Will James packs down alongside Dan Williams.
Ryan Mills, who started last week's A League opener against London Irish, moves from fly half to centre where he partners Henry Trinder.
Gloucester Rugby:
Matt Betty (Cinderford); Jack Hayes, Henry Trinder, Ryan Mills, Jonny May; James Ambrosini (Hartpury), Jordi Pasqualin; Yann Thomas, Darren Dawidiuk, Joe Reid (Birmingham Solihull); Will James, Dan Williams; Peter Buxton (capt), Akapusi Qera, Matt Cox
Replacements:
Koree Britton, Levi Smith (unattached), Harry Casson, Rob Langley, Gareth Evans, Dan Robson, James Love
