Joe Worsley replaces Chris Robshaw on the blindside flank and also takes over the captaincy of the side.
Also starting in the back row is James Haskell who is the only one of England's 22 man Test squad from last Saturday to start although Mathew Tait is named amongst the replacements.
Delon Armitage, David Strettle, Dominic Waldouck, Olly Barkley, Matt Banahan, Charlie Hodgson, Richard Wigglesworth, James Haskell, Steffon Armitage, Joe Worsley (capt), Dave Attwood, Dan Ward-Smith, Jon Golding, Lee Mears, Paul Doran-Jones.
Rob Webber, David Flatman, Chris Robshaw, Phil Dowson, Paul Hodgson, Shane Geraghty, Mathew Tait.
Peter Hynes, Nick Cummins, Will Chambers, Anthony Faingaa, Lachie Turner, Kurtley Beale, Josh Valentine, Stephen Hoiles (captain), Pat McCutcheon, Ben McCalman, Rob Simmons, Mitchell Chapman, Laurie Weeks, Tatafu Polota-Nau, Pekahou Cowan.
Huia Edmonds, James Slipper, Mark Chisholm, Matt Hodgson, Luke Burgess, Berrick Barnes, James O'Connor