Freddie Burns is set to play for the first time since recent calf surgery as he has been named to start at fly half in the A League against Saracens at Kingsholm on Monday evening.
Also set to feature on Monday evening is Fijian international winger Semi Tadulala whilst there is plenty of first team experience in the pack particularly with a front row of Pierre Capdevielle, Darren Dawidiuk and Paul Doran-Jones and in a back row including Peter Buxton and Apo Satala.
Burns has made nine appearances in total this season but last featured at Harlequins in the Guinness Premiership at the end of November before undergoing surgery to alleviate problems with cramp.
The pitch at Kingsholm was covered as soon as the Guinness Premiership fixture against Worcester Warriors on Saturday was completed.
However, with bitterly cold conditions predicted for Gloucester over the next 24 hours, should there be any doubts over the fixture taking place then the club website will be updated first.
Stefan Hawley; David Akinluyi, Mark Foster, Jack Hayes, Semi Tadulala; Freddie Burns, Charlie Simpson-Daniel; Pierre Capdevielle, Darren Dawiduik, Paul Doran-Jones; Danny Wright, Dan Williams; Peter Buxton, Richard Jenkins, Apo Satala
Ben Phillips, Yann Thomas, Shaun Knight, James Kirubirru, Marcus Brown, Danny Pointon, Mike Wilcox, Reuben Haile
Argentine international Mariano Galarza made his Gloucester Rugby debut on Sunday afternoon, and despite a disappointing reverse to Sale Sharks, the giant Puma was just glad to be making his long-awaited bow in Cherry and White.
Having skippered Scotland to a hard fought 25-13 defeat against England at Twickenham on Saturday, Greig Laidlaw spoke of the frustrations of his side doing so many good things and making real progress as a team but still finishing on the wrong end of the scoreline.
GRTV caught up with Neil McCarthy as he was unveiled as the new Head of Academy. The ex-Gloucester front rower is looking forward to getting to work with the vast arrays of talent in the Academy and across Gloucestershire.
Although understandably disappointed to see Northampton snatch a 33-33 draw with a last gasp try on Saturday, Gareth Evans told GRTV after the game that the result shows how far Gloucester have come as a team this season.
Gloucester scrum half Greig Laidlaw spoke to GRTV after the 33-33 draw with Northampton Saints on Saturday, and the Scotsman described how the hosts played some great rugby, but will rue not holding the lead which keeps them in touch with the top seven.
Although Gloucester could take many positives from the 33-33 draw with Northampton Saints on Saturday, centre Bill Meakes admitted it was a strange feeling at the final whistle with Gloucester having probably done enough to win the game.
Speaking after the 33-33 draw with Northampton Saints on Saturday, David Humphreys admitted that he was happy with many aspects of the team's performance but regretted a missed opportunity to defeat the Premiership champions.
Having confirmed a new main partner recently in Mitsubishi Motors UK, Gloucester Rugby is delighted to confirm that XBlades Sports will become the club's new kit supplier from the 2015-16 season onwards.
Hartpury U18s won the AASE league for the sixth year in a row last week beating Filton College in the Final at Allianz Park by 50 points to nil, while Bromsgrove School won their first NatWest U18 Schools Cup.