Freddie Burns is set to play for the first time since recent calf surgery as he has been named to start at fly half in the A League against Saracens at Kingsholm on Monday evening.
Also set to feature on Monday evening is Fijian international winger Semi Tadulala whilst there is plenty of first team experience in the pack particularly with a front row of Pierre Capdevielle, Darren Dawidiuk and Paul Doran-Jones and in a back row including Peter Buxton and Apo Satala.
Burns has made nine appearances in total this season but last featured at Harlequins in the Guinness Premiership at the end of November before undergoing surgery to alleviate problems with cramp.
The pitch at Kingsholm was covered as soon as the Guinness Premiership fixture against Worcester Warriors on Saturday was completed.
However, with bitterly cold conditions predicted for Gloucester over the next 24 hours, should there be any doubts over the fixture taking place then the club website will be updated first.
Stefan Hawley; David Akinluyi, Mark Foster, Jack Hayes, Semi Tadulala; Freddie Burns, Charlie Simpson-Daniel; Pierre Capdevielle, Darren Dawiduik, Paul Doran-Jones; Danny Wright, Dan Williams; Peter Buxton, Richard Jenkins, Apo Satala
Ben Phillips, Yann Thomas, Shaun Knight, James Kirubirru, Marcus Brown, Danny Pointon, Mike Wilcox, Reuben Haile
Billy Twelvetrees spoke to Russ Hargreaves of Talking Rugby at England training ahead of Sunday's huge RBS Six Nations clash with Wales at Twickenham. The centre is relishing the challenge of fronting up against a smart and talented Welsh back line.
Tim Taylor spoke to Gloucester Rugby TV after the 31 year old fly half announced that he was retiring from professional rugby. The Derby-born pivot, is excited for what the future holds for his new business ventures despite his career being cut short by a knee injury.
Dan Robson spoke to Gloucester Rugby TV at Franklin's Gardens following the 39-13 loss to Saints. The scrum-half enjoyed his battle with Lee Dickson but was gutted at the result as the Cherry and Whites did not do themselves justice, falling off in the closing stages to the league leaders.
Speaking after the game at Franklin's Gardens, Director of Rugby Nigel Davies reflected on a disappointing final quarter which saw Northampton Saints ease their way to a comfortable 39-13 win on Saturday afternoon.
Gloucester Rugby TV caught up with Gareth Evans this week ahead of the trip to Northampton Saints in the Aviva Premiership. The back rower explained his pride in his performances this season but knows there is still a lot for him to learn.
Gloucester Rugby travel to take on the table topping Northampton Saints in the Aviva Premiership on Saturday. Director of Rugby Nigel Davies is well aware of the qualities of Jim Mallinder's side, but Gloucester are the only team to defeat the Saints in the league this season.
Gloucester number eight Ben Morgan is hoping to start against Wales a week on Sunday, a team containing a number of former club team mates. He told the RFU.com website that he's looking forward to the prospect.
Second row James Hudson spoke to the club website following the 25-20 victory over Harlequins about how missed chances made things nervy late on, on what was a hugely emotional day for the Gloucester team.
Dan Murphy spoke to Gloucester Rugby TV after the win over Harlequins. The front rower touched down for the crucial second half score and expressed his delight at the performance and insisted the importance to push on from it.
There will be a trio of Gloucester Rugby players in the England Rugby starting line up for Sunday's huge clash with Wales at Twickenham. Number eight Ben Morgan is named to start with Billy Twelvetrees and Jonny May continuing in the back line.
England Under 20s have named their side to take on Wales for Friday's Under 20 Six Nations clash at Kingston Park, and Gloucester Rugby duo Billy Burns and Ross Moriarty keep their places in the starting line-up, with Jonny Hill named on the bench.