MIKE TINDALL will make his first Guinness Premiership start of the season tomorrow when he lines up alongside Anthony Allen in Gloucester's midfield for their clash against third-placed Wasps (3pm).
The England centre has been troubled by a calf injury all season and has so far made only two appearances as a replacement, against Worcester and London Irish.
But he comes into the starting line-up for the table-toppers and will make his 102nd Guinness Premiership appearance.
His return is a significant boost for head coach Dean Ryan, who said: "We have had snapshots of where we think Mike has been previously with his fitness and now we feel he is in a position to start for us in what is a hugely important game.
"We are obviously up against one of the very best teams in the Premiership which is why an individual of Mike's experience, leadership qualities and attitude are crucial.
"I think we have done exceptionally well without him but there is no doubt his return is very important."
Tindall will line-up alongside Anthony Allen, who has missed Gloucester's last two victories over Saracens and London Irish while on international duty with England.
Although he will not feature against South Africa tomorrow, Ryan is thrilled to have Gloucester's newest international available for the club again.
"We are all delighted for Anthony and he acquitted himself really well at the highest level," Ryan said. "He has the support of everyone at the club, was selected for England because he was the form number 12 in the Premiership and I hope he can continue that form for us."
Allen scored twice in the corresponding fixture last season and the centre combinations are the only changes to Gloucester's backline tomorrow.
Rory Lawson and Ryan Lamb continue at half-back, while the back three of James Simpson-Daniel, James Bailey and Willie Walker are also intact.
Gloucester have won six and drawn one of their seven Premiership games so far and Ryan has made one change to his pack following the 22-11 victory over London Irish last Friday.
Loosehead prop Nick Wood comes in for Patrice Collazo and will line-up alongside hooker Olivier Azam and tighthead Christian Califano.
Adam Eustace and Alex Brown continue in the second row, while Peter Buxton, Jake Boer - who will make his 150th Premiership appearance - and Luke Narraway complete the back row.
Buxton will skipper the side in the absence of Marco Bortolami, who is on international duty with Italy.
"Wasps have been the benchmark for the success for almost the last 10 years," Ryan said. "They have produced a raft of top-quality players through their ranks and you have to look at them and aspire to some of the success they have had.
"This side can obviously cause us problems but we are in good shape ourselves and are really looking forward to this challenge."
GLOUCESTER (v London Wasps, tomorrow, 3pm): Willie Walker; James Bailey, Mike Tindall, Anthony Allen, James Simpson-Daniel; Ryan Lamb, Rory Lawson; Nick Wood, Olivier Azam, Christian Califano, Adam Eustace, Alex Brown, Peter Buxton (capt), Jake Boer, Luke Narraway. Reps: Rob Elloway, Patrice Collazo, Jonathan Pendlebury, Adam Balding, Haydn Thomas, Jack Adams, Olly Morgan.
Speaking to the local media this week, John Afoa described the hard work that the Cherry and White have been putting in and that he is fighting fit ready for Saturday's European Rugby Challenge Cup semi final clash with Exeter Chiefs.
Gloucester Rugby face Exeter Chiefs this Saturday in the European Rugby Challenge Cup semi-final, and Charlie Sharples, who starts at full back is relishing the challenge of the big Kingsholm occasion.
Gloucester meet the Exeter Chiefs for the fourth time in competitive action this weekend, this time in the semi-final of the European Rugby Challenge Cup. Director of Rugby David Humphreys told the local media this week that this is the sort of game that Gloucester want to be involved in on a regular basis and that he and his team are looking forward to it.
Following the 29-26 loss to Harlequins, club captain Billy Twelvetrees spoke of his disappointment that the Cherry and Whites were unable to cash in on the home side's indiscipline and lose a lead on Saturday afternoon.
Number eight Gareth Evans admitted to a collective feeling of frustration as Gloucester lost narrowly at Harlequins on Saturday, but insisted that there are plenty of positives to draw upon ahead of next Saturday's European Rugby Challenge Cup semi-final at home to Exeter.
Gloucester travel to the Stoop on Saturday afternoon to take on Harlequins in the Aviva Premiership. The Cherry and Whites make just two changes from last weekend's win over Connacht as they seek consistency and continuity in their play as Nick Walshe told the local media this week.
The Gloucester Rugby Ticket office can advise that the club's initial allocation of tickets for the European Rugby Challenge Cup Final has sold out. However, the club has secured an additional allocation of tickets from EPCR which will go on sale on Monday.
Following Saturday evening's exciting European Rugby Challenge Cup semi-final victory over Exeter Chiefs, the Ticket Office at Kingsholm will be open on Sunday from 11am to 3pm for Club Members to purchase tickets for the Final.
Gloucester Rugby qualified for their first European final since 2006 as they defeated the in-form Exeter Chiefs by 30 points to 19 in a thrilling semi-final at Kingsholm on Saturday evening. The club photographer caught the best of the action.
Recent meetings between these two teams have often been thrillers, and this was no exception. It went down to the final few minutes, but Gloucester produced the goods when it mattered to qualify for the European Rugby Challenge Cup Final, beating Exeter 30-19.