The powerful pair will be key figures in a Gloucester side who are hunting top place in the southern conference of the A League competition.
They will be joined by first team squad members James Parkes at hooker, locks Mark Cornwell and Quinton Davids, Brad Davies, Marcel Garvey and Rob Thirlby in an exciting line-up.
Gloucester need to win to keep the pressure on leaders Harlequins and Fanolua and Keil will be figure heads of the side.
Last week, Gloucester beat Bristol 18-14 away to keep their title dreams alive and they will hope for another big crowd to get behind them tonight.
Emry Lewis and Alex Walker will join Parkes in the front row, while Hartpury College student Tom Rawlins will start in the back. Scrum-half James Donovan, who has impressed in his last two appearances, will start at scrum-half.
The replacement bench has yet to be finalised. Season ticket holders can gain free entry to the match and the 'kid a quid' scheme will again be operating for children under the age of 16.
GLOUCESTER v London Irish, Kingsholm, tonight 7.30pm: R. Thirlby; M. Nuttall, R. Keil, T. Fanolua, M. Garvey; B. Davies, J. Donovan; E. Lewis, J. Parkes, A. Walker, Q. Davids, M. Cornwell (capt), C. Jones, T. Rawlins, L. Halavatau. Reps to be named.
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