He has been out of action since the middle of August after suffering a set-back in his bid to recover from medial ligament damage picked up against Bath in the Premiership last season.
But he returned to full training this week and is expected to be included when Gloucester start their campaign with another west country derby on Monday night.
Although the team has yet to be confirmed, it is likely to include lock Adam Eustace, hooker Rob Elloway and flanker James Merriman as Gloucester aim to continue their excellent run in the competition.
"Potentially, we have an outstanding squad of players to select from and we obviously want to try and continue our success of recent seasons," said assistant Academy manager Mark Cornwell.
"With the calibre of players we have available for selection, we obviously believe we can do well in this competition.
"It is always a fantastic opportunity when you play Bath and we will be looking to get off to a really good start."
Gloucester start their home matches in the Guinness A League on Monday, September 25 against Saracens at 7.30pm.
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