London Irish have made five changes to the starting line-up for Gloucester's visit to the Madejski Stadium on Saturday 26 March (kick off 5pm).
The changes come on the back of the defeat to Leicester two weeks ago. Scott Staniforth returns on the right wing having recovered from injury, Geoff Appleford starts at outside centre on his return from playing for England in Hong Kong, and Darren Edwards takes over at scrum half.
Among the forwards Robbie Russell comes in at hooker after being with Scotland's squad in the Six Nations and Bob Casey returns in the second row after playing for the Ireland A team.
Irish are missing Delon Armitage (leg), Peter Poulos (knee) and Richard Skuse (neck) through injury.
Commenting on the game, Gary Gold, London Irish's head coach, said: "We have four Zurich Premiership games to go and because we are only 12 points adrift of fourth placed Bath, there's still time for us to make something of our season starting on Saturday with the visit of Gloucester.
"Despite all the recent setbacks, we know we can figure in the end-of-season play-offs and make the Heineken Cup next year. That remains our goal."
15. Michael Horak*; 14. Scott Staniforth*; 13. Geoff Appleford*; 12. Mike Catt*; 11. Justin Bishop*; 10. Barry Everitt; 9. Darren Edwards; 1. Neal Hatley; 2. Robbie Russell*; 3. Rob Hardwick*; 4. Ryan Strudwick (captain); 5. Bob Casey*; 6. Paul Gustard; 7. Kieron Dawson*; 8. Roland Reid*.
Replacements: 16. Doug Wheatley; 17. Adrian Flavin; 18. Nick Kennedy; 19. Declan Danaher; 20. Nils Mordt; 21. Mark Mapletoft*; 22. Paul Hodgson.
* Denotes international
Billy Burns and Man of the Match Richard Hibbard spoke to GRTV after the 41-0 win in Treviso, on a day when preparations weren't ideal. They felt the team's attitude was key and also praised the travelling support.
Matt Scott was again in impressive try scoring form for the Cherry and Whites on Saturday, and the Scotsman laid praise on his fellow backs for their attacking skills in a big 55-19 win over Worcester Warriors
Jonny May spilled blood for the cause on Saturday, before going on to score the first try in the 55-19 Aviva Premiership victory over Worcester. He told GRTV that the win was a reward for the hard work the squad have been putting in.
Gloucester Rugby face their second tough Aviva Premiership fixture in six days when they take on Worcester Warriors at Kingsholm on Saturday (kick off 3pm). Head Coach Laurie Fisher is expecting a massive challenge from one of Gloucester's local rivals.
It was a frustrated and bitterly disappointed Willi Heinz who spoke to GRTV following the 12-13 reverse to Northampton Saints on New Year's Day. The skipper thanked the fans for their incredible support on a day when Gloucester couldn't quite get the job done.
A postponement, a rescheduling and a 3-hour wait on the tarmac threatened to disrupt Gloucester's trip to Treviso, but a short relocation and delay did nothing to prevent a six-try thumping over Treviso on Saturday afternoon.
It was a case of triumph over adversity for Gloucester in Italy this weekend, their pre-match preparations ruined by a relocation of the game. However, it was a job well done for the Cherry and Whites who defeated Benetton Treviso 41-0 in freezing conditions in Italy to top pool one.