London Irish have made five changes to the starting line-up for Gloucester's visit to the Madejski Stadium on Saturday 26 March (kick off 5pm).
The changes come on the back of the defeat to Leicester two weeks ago. Scott Staniforth returns on the right wing having recovered from injury, Geoff Appleford starts at outside centre on his return from playing for England in Hong Kong, and Darren Edwards takes over at scrum half.
Among the forwards Robbie Russell comes in at hooker after being with Scotland's squad in the Six Nations and Bob Casey returns in the second row after playing for the Ireland A team.
Irish are missing Delon Armitage (leg), Peter Poulos (knee) and Richard Skuse (neck) through injury.
Commenting on the game, Gary Gold, London Irish's head coach, said: "We have four Zurich Premiership games to go and because we are only 12 points adrift of fourth placed Bath, there's still time for us to make something of our season starting on Saturday with the visit of Gloucester.
"Despite all the recent setbacks, we know we can figure in the end-of-season play-offs and make the Heineken Cup next year. That remains our goal."
15. Michael Horak*; 14. Scott Staniforth*; 13. Geoff Appleford*; 12. Mike Catt*; 11. Justin Bishop*; 10. Barry Everitt; 9. Darren Edwards; 1. Neal Hatley; 2. Robbie Russell*; 3. Rob Hardwick*; 4. Ryan Strudwick (captain); 5. Bob Casey*; 6. Paul Gustard; 7. Kieron Dawson*; 8. Roland Reid*.
Replacements: 16. Doug Wheatley; 17. Adrian Flavin; 18. Nick Kennedy; 19. Declan Danaher; 20. Nils Mordt; 21. Mark Mapletoft*; 22. Paul Hodgson.
* Denotes international
Speaking immediately after the 28-6 victory over Harlequins on Saturday, Tom Savage praised his team mates for building on their fast start. The second row admitted there's still lots of work to do for Gloucester but that the side are heading in the right direction.
Speaking to GRTV after the game, Director of Rugby David Humphreys spoke of his delight in securing a 28-6 win over Harlequins at Kingsholm. He hailed the home side's defence which they were quick to turn into attack.
Speaking to the local media, Bill Meakes this week explained how he was relishing the challenge against Harlequins at Kingsholm, and that he is enjoying the opportunity to develop his game time, and repaying the faith from the Cherry and White coaches
Gloucester look to build upon the local derby win over Bath last weekend with Harlequins the visitors to Kingsholm on Saturday (kick off 3pm). Director of Rugby David Humphreys is expecting a close game with the two teams well matched, although it may not be a 78 point thriller like the last time the two teams met.
Named Man of the Match by BT Sport, scrum-half Willi Heinz said after the 15-11 win at Bath on Friday evening that it was a pretty happy Gloucester dressing room and reward for a lot of hard work put in during the week leading up to the game.
Speaking after the 15-11 win over Bath at the Rec on Friday evening, David Humphreys heaped praise on his players, pointing out how they had bounced back after last week's tough defeat to overcome a rough start before controlling the game and earning the win.
Gloucester Rugby hooker Richard Hibbard spoke to the local media this week as the Cherry and Whites prepare to face Bath Rugby in the Aviva Premiership. The Welshman is ready to bounce back at The Rec.
Speaking to the local media about the local derby against Bath at the Rec on Friday evening, Director of Rugby David Humphreys acknowledged that it will be a tough encounter but hugely exciting at the same time and one the squad are looking forward to.
After a disappointing opening weekend loss to their Scottish counterparts, England U20s will be eager to bounce back in Italy this evening, with Gloucester flyer Mat Protheroe set to pull the strings from fly half.
Gloucester Rugby make just the one change to the starting line up that won at Bath last Friday evening, flanker Matt Kvesic restored to the starting XV as the Cherry and Whites welcome Harlequins to Kingsholm in the Aviva Premiership on Saturday (kick off 3pm).
The Early Bird deadline for ticket purchases for the Aviva Premiership fixture against Harlequins on Saturday will expire at 6:30pm on Thursday evening, with tickets already limited for one area of Kingsholm.