London Irish have made five changes to the starting line-up for Gloucester's visit to the Madejski Stadium on Saturday 26 March (kick off 5pm).
The changes come on the back of the defeat to Leicester two weeks ago. Scott Staniforth returns on the right wing having recovered from injury, Geoff Appleford starts at outside centre on his return from playing for England in Hong Kong, and Darren Edwards takes over at scrum half.
Among the forwards Robbie Russell comes in at hooker after being with Scotland's squad in the Six Nations and Bob Casey returns in the second row after playing for the Ireland A team.
Irish are missing Delon Armitage (leg), Peter Poulos (knee) and Richard Skuse (neck) through injury.
Commenting on the game, Gary Gold, London Irish's head coach, said: "We have four Zurich Premiership games to go and because we are only 12 points adrift of fourth placed Bath, there's still time for us to make something of our season starting on Saturday with the visit of Gloucester.
"Despite all the recent setbacks, we know we can figure in the end-of-season play-offs and make the Heineken Cup next year. That remains our goal."
15. Michael Horak*; 14. Scott Staniforth*; 13. Geoff Appleford*; 12. Mike Catt*; 11. Justin Bishop*; 10. Barry Everitt; 9. Darren Edwards; 1. Neal Hatley; 2. Robbie Russell*; 3. Rob Hardwick*; 4. Ryan Strudwick (captain); 5. Bob Casey*; 6. Paul Gustard; 7. Kieron Dawson*; 8. Roland Reid*.
Replacements: 16. Doug Wheatley; 17. Adrian Flavin; 18. Nick Kennedy; 19. Declan Danaher; 20. Nils Mordt; 21. Mark Mapletoft*; 22. Paul Hodgson.
* Denotes international
Speaking to GRTV in front of the iconic Clifton Suspension Bridge, Henry Trinder explained how important the West Country Challenge Cup is going to be for the Cherry and Whites in their preseason preparations.
Speaking to GRTV at preseason training this Tuesday, new signing Willi Heinz gave an update on his recovery from a leg injury and expressed his enjoyment since his arrival in new surroundings with Gloucester Rugby.
Speaking to GRTV after the 22-23 defeat against Bordeaux-Begles which denied Gloucester a place in next season's European Rugby Champions Cup, Nick Wood rued the momentary lapse in concentration which allowed the French side to snatch victory from the jaws of defeat.
As Gloucester prepare for their 39th game of the season, against Bordeaux-Begles at Sixways on Sunday, David Humphreys told the local media that this week has been all about getting the players mentally and physically ready after a tough game against Connacht last Sunday.
Gloucester Rugby and Scotland scrum half Greig Laidlaw is gearing up for Rugby World Cup with his international teammates, and speaking to the assembled media this week, Laidlaw is excited to be in familiar surroundings at the showcase tournament.
With 50 days to go until Rugby World Cup 2015 gets underway several of the nations that are set to take to the Kingsholm Stadium field during the pool stages were in action in Toronto in Round Three of the Pacific Nations Cup.