Phil Vickery takes over the Gloucester captaincy for Saturday's 13,000 sell-out West Country derby against Bath at Kingsholm.
28 year-old Vickery leads from the front row alongside Welsh international hooker Mefin Davies and England U21 prop Nick Wood.
Adam Eustace returns to the second row in place of Mark Cornwell. James Forrester is named in the back-row and teams up with Andy Hazell and Adam Balding, with Jake Boer being dropped from the squad.
Henry Paul moves to stand-off in place of Duncan McRae, who misses out through injury. Marcel Garvey claims back the number 14 shirt after missing the last two games with mumps.
James Simpson-Daniel starts at outside centre, with Tongan Seti Kiole starting on the other wing, making it six changes to the starting line-up following Gloucester's last outing away at NEC Harlequins.
Players unavailable include Gary Powell (ankle), Chris Fortey (ankle), Olivier Azam (shoulder), Simon Amor (shoulder), Ryan Lamb (England U19s) and Nathan Mauger, who has flown back to New Zealand following a family bereavement.
15. Jon Goodridge
14. Marcel Garvey
13. James Simpson-Daniel
12. Terry Fanolua
11. Seti Kiole
10. Henry Paul
9. Andy Gomarsall
1. Nick Wood
2. Mefin Davies
3. Phil Vickery (c)
4. Adam Eustace
5. Alex Brown
6. James Forrester
7. Andy Hazell
8. Adam Balding
16. Noel Curnier
17. Terry Sigley
18. Mark Cornwell
19. Peter Buxton
20. James Merriman
21. Alex Page
22. James Bailey
Speaking to the media following the 31-33 West Country Challenge Cup defeat to Exeter Chiefs at the Memorial Stadium, Director of Rugby David Humphreys was full of praise for his side's battling qualities in a bruising encounter but concerned about the injuries picked up.
The West Country Challenge Cup fixture against the Exeter Chiefs at the Memorial Stadium in Bristol on Saturday (kick off 3pm) will be Gloucester's last chance to work on things like new combinations says Director of Rugby, David Humphreys.
Speaking after the 30-21 West Country Challenge Cup defeat at Bath, Director of Rugby David Humphreys spoke of the improvements his team are making as preseason progresses but acknowledges that there is still work to do ahead of the start of the Aviva Premiership.
Speaking to the local media ahead of Saturday's trip to Bath Rugby in the West Country Challenge Cup, front rower Nick Wood spoke of the hard work put in across the extended preseason and highlighted the competition for front row spots in the squad.
Gloucester have named a 30 man squad for the latest round of West Country Challenge Cup action against Bath on Saturday, with Director of Rugby David Humphreys stressing the need to keep an eye on player workload ahead of what will be a long, tough season.
Describing the 50-7 West Country Challenge Cup win over Bath on Sunday as a '...good hit out...', wing Charlie Sharples admitted that it had been a good opportunity to put into practice things that the squad have been trying out in training in recent weeks.
Speaking to the local media after the 50-7 victory over Bath Rugby on Sunday, David Humphreys was happy with his squad's effort, with the most important aspect being the game time earned by his players.
Gloucester make wholesale changes to the side that started at Exeter last Saturday as they prepare to take on Bath at the Memorial Stadium, Bristol on Sunday in the West Country Challenge Cup (kick off 3pm). The Director of Rugby told GRTV that the players are raring to go and that he's looking forward to seeing different combinations in action.