Phil Vickery takes over the Gloucester captaincy for Saturday's 13,000 sell-out West Country derby against Bath at Kingsholm.
28 year-old Vickery leads from the front row alongside Welsh international hooker Mefin Davies and England U21 prop Nick Wood.
Adam Eustace returns to the second row in place of Mark Cornwell. James Forrester is named in the back-row and teams up with Andy Hazell and Adam Balding, with Jake Boer being dropped from the squad.
Henry Paul moves to stand-off in place of Duncan McRae, who misses out through injury. Marcel Garvey claims back the number 14 shirt after missing the last two games with mumps.
James Simpson-Daniel starts at outside centre, with Tongan Seti Kiole starting on the other wing, making it six changes to the starting line-up following Gloucester's last outing away at NEC Harlequins.
Players unavailable include Gary Powell (ankle), Chris Fortey (ankle), Olivier Azam (shoulder), Simon Amor (shoulder), Ryan Lamb (England U19s) and Nathan Mauger, who has flown back to New Zealand following a family bereavement.
15. Jon Goodridge
14. Marcel Garvey
13. James Simpson-Daniel
12. Terry Fanolua
11. Seti Kiole
10. Henry Paul
9. Andy Gomarsall
1. Nick Wood
2. Mefin Davies
3. Phil Vickery (c)
4. Adam Eustace
5. Alex Brown
6. James Forrester
7. Andy Hazell
8. Adam Balding
16. Noel Curnier
17. Terry Sigley
18. Mark Cornwell
19. Peter Buxton
20. James Merriman
21. Alex Page
22. James Bailey
Speaking after the game, Charlie Sharples described it as 'the win that has eluded us.' The winger stressed that Gloucester had stayed positive after the first couple of weeks of the Aviva Premiership season and the 26-13 victory over Sale was a result of that focus.
Gloucester Rugby picked up their first win of the new Aviva Premiership season on Friday night, easing to a 26-13 win on the road at Sale Sharks. Director of Rugby David Humphreys was full of praise for his players on the night.
Defence Coach Jonny Bell was on media duties ahead of the Aviva Premiership fixture at Sale Sharks on Friday evening, and spoke about where Gloucester find themselves in terms of their form at the moment as well as how he's viewing their defensive displays so far.
Callum Braley, who skippered Gloucester United to a 22-19 Aviva Premiership A League win over Saracens Storm on Monday evening, paid tribute to his forwards and the younger players in what he described as not the prettiest of wins.
Gloucester Wheelchair Rugby Club hosted their second invitational tournament on Sunday 18th September. Teams from the South Wales Ospreys, the Southampton Sharks, Stoke Mandeville Maulers and the West Country Hawks travelled to Leisure @ in Cheltenham and played a 'round robin' sequence of games.
Kingsholm will play host to the inaugural Mitsubishi Motors Hybrid Cup on Sunday 9 October (kick off 3pm), where the Gloucester Rugby Heroes meet the Salford Red Devils Legends in a cross-code exhibition clash with legends of both games set to grace the Kingsholm turf again.
Gloucester Rugby have been rolling back the years, dusting off their old childhood memorabilia and reminiscing about their first grassroots amateur sports clubs in support of this year's Aviva Community Fund.