Phil Vickery takes over the Gloucester captaincy for Saturday's 13,000 sell-out West Country derby against Bath at Kingsholm.
28 year-old Vickery leads from the front row alongside Welsh international hooker Mefin Davies and England U21 prop Nick Wood.
Adam Eustace returns to the second row in place of Mark Cornwell. James Forrester is named in the back-row and teams up with Andy Hazell and Adam Balding, with Jake Boer being dropped from the squad.
Henry Paul moves to stand-off in place of Duncan McRae, who misses out through injury. Marcel Garvey claims back the number 14 shirt after missing the last two games with mumps.
James Simpson-Daniel starts at outside centre, with Tongan Seti Kiole starting on the other wing, making it six changes to the starting line-up following Gloucester's last outing away at NEC Harlequins.
Players unavailable include Gary Powell (ankle), Chris Fortey (ankle), Olivier Azam (shoulder), Simon Amor (shoulder), Ryan Lamb (England U19s) and Nathan Mauger, who has flown back to New Zealand following a family bereavement.
15. Jon Goodridge
14. Marcel Garvey
13. James Simpson-Daniel
12. Terry Fanolua
11. Seti Kiole
10. Henry Paul
9. Andy Gomarsall
1. Nick Wood
2. Mefin Davies
3. Phil Vickery (c)
4. Adam Eustace
5. Alex Brown
6. James Forrester
7. Andy Hazell
8. Adam Balding
16. Noel Curnier
17. Terry Sigley
18. Mark Cornwell
19. Peter Buxton
20. James Merriman
21. Alex Page
22. James Bailey
Ahead of Friday evening's Aviva Premiership fixture away at London Welsh, Head Coach Laurie Fisher told the local media that he feels that Gloucester are making improvements each and every week but that there's still plenty of work to do.
Speaking to GRTV on Monday night, Pete Buxton was thrilled with the spirit shown by the Gloucester United squad as they overturned a twenty-one point deficit in the second half to overcome Bristol Rugby.
Scrum half Callum Braley was a try scorer in Gloucester United's 30-27 win over Bristol United in the Aviva Premiership A League on Monday evening and, after the game, paid tribute to his team mates for hanging in there and fighting back to get the win.
Skipper Billy Twelvetrees admitted that the Gloucester squad were disappointed and frustrated after losing at home to Exeter, regretting that Gloucester's own errors had given the Chiefs the upper hand.
Gloucester Rugby is rightly proud of the work that it does within the community and is delighted to confirm that it will be working with Gloucestershire Young Carers and Pied Piper as its two chosen charities this season.