Gloucester's Andy Hazell starts from the bench for England against Ireland in the RBS Six Nations clash in Dublin on Sunday.
England head coach Andy Robinson makes only one change to the starting XV and three changes to the bench.
22 year-old Bath prop Matt Stevens makes his debut in England's starting line up at tight head prop, with fellow Bath prop Duncan Bell on the bench.
Stevens, who has been in great form for Bath in the Zurich Premiership, earned his first two England caps last summer against the All Blacks in New Zealand and is part of England's 30 man squad for the RBS 6 Nations championship.
Robinson commented that Stevens' debut in the starting XV was well deserved. "I'm thrilled for Matt and am confident he will grasp this opportunity and make his mark against Ireland.
"He has impressed in training and has been building up to this for some time now."
As well as Duncan Bell coming onto the bench, two Leicester Tigers players have also been brought in by the head coach - centre Ollie Smith and fly half Andy Goode.
Robinson added: "All three players have shown outstanding form of late, most recently in the England A win against France A and for their club. Selection beckons when players demonstrate such consistent ability.
"This game against Ireland will be massive. We recognise it's a must-win game for us this season."
England confirmed that Sale Sharks prop Andrew Sheridan was not considered for selection because of a cut he received when playing last Friday to the back of his ankle.
16 Andy Titterrell (Sale Sharks)
17 Duncan Bell (Bath)
18 Steve Borthwick (Bath)
19 Andy Hazell (Gloucester)
20 Matt Dawson (London Wasps)
21 Andy Goode (Leicester Tigers)
22 Ollie Smith (Leicester Tigers)
Previewing Friday evening's local derby at Bristol, Interim Head Coach Jonny Bell told the local media that Gloucester's preparations have gone well and that the whole squad is united in trying to finish the season on a high.
Speaking to GRTV this week, Acting Head Coach Jonny Bell spoke of his pleasure in the efforts and intensity in training from the squad after a tricky few weeks. The team were preparing for big games with Bristol and Cardiff in coming weeks.
Willi Heinz was understandably and visibly disappointed when he spoke to GRTV after the 27-30 home defeat to Harlequins, apologising to the home support as the game slipped away after seemingly having the game under control.
Speaking to the local media this week, Scottish centre Matt Scott spoke of the squad's determination to put in a big home performance against Harlequins, with vital points up for grabs in the hunt for a Top Six spot this Saturday (KO 3pm)
Looking ahead to Saturday's Aviva Premiership fixture at home to Harlequins (kick off 3pm), Head Coach Laurie Fisher told the local media that Gloucester will need to be on top of their game in a match which has big implications in terms of top six ambitions.
A big few days for the Gloucester-Hartpury Women side. First came the news that the team will compete in Women's Super Rugby next season, and on Saturday the team will play Worcester Ladies IIs at Kingsholm. Centre Hannah Jones and wing Michelle Ruddock spoke to GRTV this week to reflect on events.
Missing so many starters, and up against a team fighting for their Premiership existence, Gloucester did what had to be done at Ashton Gate on Friday evening battling their way to a 32-14 Aviva Premiership win over Bristol Rugby.