Gloucester's Andy Hazell starts from the bench for England against Ireland in the RBS Six Nations clash in Dublin on Sunday.
England head coach Andy Robinson makes only one change to the starting XV and three changes to the bench.
22 year-old Bath prop Matt Stevens makes his debut in England's starting line up at tight head prop, with fellow Bath prop Duncan Bell on the bench.
Stevens, who has been in great form for Bath in the Zurich Premiership, earned his first two England caps last summer against the All Blacks in New Zealand and is part of England's 30 man squad for the RBS 6 Nations championship.
Robinson commented that Stevens' debut in the starting XV was well deserved. "I'm thrilled for Matt and am confident he will grasp this opportunity and make his mark against Ireland.
"He has impressed in training and has been building up to this for some time now."
As well as Duncan Bell coming onto the bench, two Leicester Tigers players have also been brought in by the head coach - centre Ollie Smith and fly half Andy Goode.
Robinson added: "All three players have shown outstanding form of late, most recently in the England A win against France A and for their club. Selection beckons when players demonstrate such consistent ability.
"This game against Ireland will be massive. We recognise it's a must-win game for us this season."
England confirmed that Sale Sharks prop Andrew Sheridan was not considered for selection because of a cut he received when playing last Friday to the back of his ankle.
16 Andy Titterrell (Sale Sharks)
17 Duncan Bell (Bath)
18 Steve Borthwick (Bath)
19 Andy Hazell (Gloucester)
20 Matt Dawson (London Wasps)
21 Andy Goode (Leicester Tigers)
22 Ollie Smith (Leicester Tigers)
As Gloucester prepare for their 39th game of the season, against Bordeaux-Begles at Sixways on Sunday, David Humphreys told the local media that this week has been all about getting the players mentally and physically ready after a tough game against Connacht last Sunday.
Speaking to GRTV after the 40-32 victory over Connacht on Sunday, skipper Billy Twelvetrees explained that Gloucester had had to learn to be patient and cut out the errors to earn the win and progress to next weekend's final play-off against Bordeaux-Begles.
Jonny May's superb late score capped a thrilling 40-32 European play-off win over Connacht on Sunday. The winger spoke afterwards of his team's character and spirit as he looked ahead to one more week of rugby.
Speaking to GRTV this afternoon, Director of Rugby David Humphreys hailed the 'never say die' attitude of the team, after despite not being at their best, fighting back to take a 40-32 win after extra time over Connacht.
Jonny May continues on the wing on Sunday as Connacht come to town, and the England wing explains to the local media this week that he is delighted with his form and is looking forward to taking on Pat Lam's men.
Following the recent announcement that XBlades were to become the club's new kit and leisurewear partner, Gloucester Rugby can today (Tuesday 30 June) confirm the opening of a new retail unit, based at Gloucester Quays Outlet Centre, as well as the launch of a brand new online shop.