Gloucester's Andy Hazell starts from the bench for England against Ireland in the RBS Six Nations clash in Dublin on Sunday.
England head coach Andy Robinson makes only one change to the starting XV and three changes to the bench.
22 year-old Bath prop Matt Stevens makes his debut in England's starting line up at tight head prop, with fellow Bath prop Duncan Bell on the bench.
Stevens, who has been in great form for Bath in the Zurich Premiership, earned his first two England caps last summer against the All Blacks in New Zealand and is part of England's 30 man squad for the RBS 6 Nations championship.
Robinson commented that Stevens' debut in the starting XV was well deserved. "I'm thrilled for Matt and am confident he will grasp this opportunity and make his mark against Ireland.
"He has impressed in training and has been building up to this for some time now."
As well as Duncan Bell coming onto the bench, two Leicester Tigers players have also been brought in by the head coach - centre Ollie Smith and fly half Andy Goode.
Robinson added: "All three players have shown outstanding form of late, most recently in the England A win against France A and for their club. Selection beckons when players demonstrate such consistent ability.
"This game against Ireland will be massive. We recognise it's a must-win game for us this season."
England confirmed that Sale Sharks prop Andrew Sheridan was not considered for selection because of a cut he received when playing last Friday to the back of his ankle.
16 Andy Titterrell (Sale Sharks)
17 Duncan Bell (Bath)
18 Steve Borthwick (Bath)
19 Andy Hazell (Gloucester)
20 Matt Dawson (London Wasps)
21 Andy Goode (Leicester Tigers)
22 Ollie Smith (Leicester Tigers)
Speaking straight after the game, skipper Billy Twelvetrees told GRTV that losing at home to Bath, in front of a tremendous home support, was desperately disappointing and that the whole team were hurting in the dressing room.
Speaking to the local media this week, Richard Hibbard expressed his excitement ahead of the West Country derby and that there is an extra spring in the step of the Cherry and Whites ahead of the tough challenge.
With such a short turnaround between the two games, and Gloucester looking to reintegrate several players into the line-up after the Autumn international series, Tom Savage told GRTV that the Cherry and Whites will keep changes to a minimum for the European Rugby Challenge Cup game in Zebre on Saturday.
On a tough evening at Kingsholm, Gloucester could escape neither a suffocating Bath defence, nor the whistle of referee Greg Garner as six penalties and a penalty try paved the way to a 39-16 win for the visitors.