Gloucester's Andy Hazell starts from the bench for England against Ireland in the RBS Six Nations clash in Dublin on Sunday.
England head coach Andy Robinson makes only one change to the starting XV and three changes to the bench.
22 year-old Bath prop Matt Stevens makes his debut in England's starting line up at tight head prop, with fellow Bath prop Duncan Bell on the bench.
Stevens, who has been in great form for Bath in the Zurich Premiership, earned his first two England caps last summer against the All Blacks in New Zealand and is part of England's 30 man squad for the RBS 6 Nations championship.
Robinson commented that Stevens' debut in the starting XV was well deserved. "I'm thrilled for Matt and am confident he will grasp this opportunity and make his mark against Ireland.
"He has impressed in training and has been building up to this for some time now."
As well as Duncan Bell coming onto the bench, two Leicester Tigers players have also been brought in by the head coach - centre Ollie Smith and fly half Andy Goode.
Robinson added: "All three players have shown outstanding form of late, most recently in the England A win against France A and for their club. Selection beckons when players demonstrate such consistent ability.
"This game against Ireland will be massive. We recognise it's a must-win game for us this season."
England confirmed that Sale Sharks prop Andrew Sheridan was not considered for selection because of a cut he received when playing last Friday to the back of his ankle.
16 Andy Titterrell (Sale Sharks)
17 Duncan Bell (Bath)
18 Steve Borthwick (Bath)
19 Andy Hazell (Gloucester)
20 Matt Dawson (London Wasps)
21 Andy Goode (Leicester Tigers)
22 Ollie Smith (Leicester Tigers)
Matt Scott made his first appearance in Cherry and White on Saturday afternoon, and despite a narrow loss to Leinster, the Scotsman highlighted a lot to be pleased about after the first hit out of the new season.
Lloyd Evans will assume a senior role in the Gloucester Rugby squad as they head to Franklin's Gardens for the Singha Premiership Rugby 7s on Friday evening. The exciting Academy fly half spoke to GRTV this week ahead of the season curtain-raiser.
Summer signing Matt Scott met with the local media for the first time this week and said that he's settling in well at Gloucester, that hopes are high for the forthcoming season and that skipper Greig Laidlaw had done a good sales pitch when it came to him signing!
Olly Morgan is heading up Gloucester's Singha Premiership 7s once again this summer and, with the start of the tournament just around the corner, he's looking for some of the club's younger players to make the most of the playing time and the exposure it offers.
The Cherry & Whites are now in their second full week of preseason ahead of the new season, and GRTV caught up with the new Head of Strength & Conditioning Dan Tobin to chat about what is in store, and his first impressions of the club.
Speaking exclusively to GRTV before Wales set off for Twickenham on Friday afternoon, Ross Moriarty chatted about the prospect of taking on England on Sunday as well as the challenge of the subsequent tour to New Zealand.
Brighton is the venue of choice for England this week as the squad have reported for a training camp to prepare for the upcoming international against Wales. GRTV caught up with Gloucester's Matt Kvesic after the first day's training.
Gloucester Rugby has always been very active in the local community, promoting grassroots rugby and delivering programmes to underprivileged children, and recently we received the news that we had achieved registered charity status to allow us to continue what we've been doing and grow our programmes across the county.
Gloucester Rugby are joining forces with main club partners Mitsubishi Motors in scrumming down with legends of rugby union and rugby league for a hybrid match with aims to raise thousands of pounds for charity at the same time.