Gloucester's Olly Morgan misses out on this weekend's England U21 game against France at Franklin's Gardens (Fri 11 Feb, kick off 7.30pm).
The 19 year-old full-back played in last weekend's clash against Wales, but had a slight problem with his hamstring this week. Morgan has only just returned from a lengthy period out with a wrist injury, and is rested as a precaution.
Elsewhere in the England representative sides, Gloucester's Ryan Lamb starts at scrum-half for England U19s against their French counterparts. The U19s play France on Friday 11 February at Doncaster RFC, kick off 7pm.
Looking ahead to England's U21s clash against the French coach Jim Mallinder said: "Despite the disappointment of last week, the mood has been really positive all week. It's early days yet but things are starting to come together.
"We're delighted with the way we came back to score three tries in the second half last week and our aim this match is to continue our progress and build on that second half performance."
Assistant coach Nigel Redman added: "Falcons hooker Stuart Mackie has been called up to the bench to replace Neil Briggs and Saracens' David Seymour has been selected at open-side flanker on the back of regular performances in the premiership this season."
After a series of good performances for his club Northampton Saints, Paul Diggin makes his international U21 debut in the number 14 shirt. "Paul's performances in the last two Saints games mean he has been selected in this side on merit and he fully deserves this chance to impress."
England U21 team to play France
Friday 11th February, Northampton Saints, kick off 7.30pm
15. Ross Broadfoot, Leicester Tigers
14. Paul Diggin, Northampton Saints
13. Matt Cornwell, Leicester Tigers
12. Simon Whatling, Worcester
11. Tom Varndell, Leicester Tigers
10. Ryan Davis, Bath
9. Ben Foden, Sale Sharks
1. Aston Croall, Saracens
2. David Ward, Bath
3. Matt Hampson, Leicester Tigers
4. Richard Blaze, Worcester
5. Dan Smith, Bath
6. Tom Rees, London Wasps (captain)
7. David Seymour, Saracens
8. Chris Goodman, Bath
16. Stuart Mackie, Newcastle Falcons
17. Michael Cusack, Leeds Tykes
18. Tom Ryder, Leicester Tigers
19. James Haskell, London Wasps
20. Lee Dickson, Newcastle Falcons
21. James Wellwood, London Wasps
22. Tom Biggs, Leeds Tykes
Speaking with the local media before the Gloucester team set off on the long trip north to Newcastle, Director of Rugby David Humphreys discussed his team selection and stated that Friday night's meeting will be a challenging one.
Speaking to the local media on Thursday, Matt Kvesic was looking forward to the trip to Newcastle Falcons, and the captain is looking to lead from the front with plenty for the Cherry and Whites to work on.
Gloucester saw a 12-0 lead overturned by Harlequins on Friday night as the visitors ran out 22-15 winners. After the game, Director of Rugby David Humphreys spoke about missed opportunities on the night.
Speaking to the local media on Thursday, James Hudson explained his excitement for tonight's game with Harlequins and that he is backing the Cherry and White squad to impress during the next set of Aviva Premiership games.
20 year old Lewis Ludlow was one of Gloucester's young guns who contributed hugely to the 18-9 LV= Cup win at London Welsh on Sunday afternoon. After the game, he praised his team mates for the massive team effort by an inexperienced side.
There are three changes to Gloucester Rugby's starting line-up for Friday evening's Aviva Premiership fixture away at Newcastle Falcons. Steve McColl will make his first Premiership start for the club.