Bristol travel to Gloucester for Saturday's 13,000 sell-out.
Bristol Shoguns have made one change to their line-up for Saturday's Powergen Cup clash, bringing in former Scottish international David Hilton for Alex Clarke at loosehead prop.
Bristol coach Richard Hill, the former Gloucester director of rugby, said: "The front row with Dave Hilton coming in is just a normal rotational change. Alex Clarke and Dave Hilton have been playing equally well so, what we tend to do, is give them two games each.
"Jason Hobson keeps his place. Darren Crompton bruised his ribs at London Welsh so missed Sedgley Park and is not quite right for this one.
"Bernardo Stortoni is also still out with a tweak to a knee ligament which isn't quite right for this weekend but he'll be ok for next weekend. So, Matt Salter, Darren Crompton and Bernardo Stortoni are the three injuries we have on our list but all three we hope are just one or two weeks away.
"Unusually we've had little or no discussion about Gloucester this week. We're planning for the next two to three weeks of the league programme and Exeter particularly on Feb 5th. It's been good in a way because I haven't heard a lot of talk about Gloucester.
"The first 20 minutes will be absolutely crucial because they'll have had a kick up the backside, I imagine. Words like 'The Gloucester forwards have lost the respect of the Kingsholm crowd' that have come out of the mouth of Nigel Melville will have hurt.
"We know we've got a huge job and they'll have been stung into action. But, if we can be close to them after 20 minutes, I think the crowd will get a little bit restless and one or two doubts might creep in. That's all we can hope for.
"It'll either be completely over for us after 20 minutes or there'll be a very interesting game in prospect. If we do make it to the Premiership and we're looking to retain players, we have to be sure that they're capable of taking it up to the next level."
Recent signings, scrum half Hentie Martens, fly-half Mark Woodrow and flanker Craig Short are all 'Cup-tied'
Bristol Shoguns team
15 Sean Marsden
14 Marko Stanojevic
13 Rob Higgitt
12 Sam Cox
11 Luke Nabaro
10 Jason Strange
9 Ross Blake
1 Dave Hilton
2 Saul Nelson
3 Jason Hobson
4 Ed Pearce
5 Ollie Hodge
6 Chris Morgan
7 Joe El-Abd (Capt.)
8 Jim Brownrigg
16 Greg Nicholls
17 Jonathan Pritchard
18 Adam Billig
19 Alex Clarke
20 Neil Clark
21 Rik Martin-Redman
22 Olly Kohn
Previewing Friday evening's local derby at Bristol, Interim Head Coach Jonny Bell told the local media that Gloucester's preparations have gone well and that the whole squad is united in trying to finish the season on a high.
Speaking to GRTV this week, Acting Head Coach Jonny Bell spoke of his pleasure in the efforts and intensity in training from the squad after a tricky few weeks. The team were preparing for big games with Bristol and Cardiff in coming weeks.
Willi Heinz was understandably and visibly disappointed when he spoke to GRTV after the 27-30 home defeat to Harlequins, apologising to the home support as the game slipped away after seemingly having the game under control.
Speaking to the local media this week, Scottish centre Matt Scott spoke of the squad's determination to put in a big home performance against Harlequins, with vital points up for grabs in the hunt for a Top Six spot this Saturday (KO 3pm)
Looking ahead to Saturday's Aviva Premiership fixture at home to Harlequins (kick off 3pm), Head Coach Laurie Fisher told the local media that Gloucester will need to be on top of their game in a match which has big implications in terms of top six ambitions.
A big few days for the Gloucester-Hartpury Women side. First came the news that the team will compete in Women's Super Rugby next season, and on Saturday the team will play Worcester Ladies IIs at Kingsholm. Centre Hannah Jones and wing Michelle Ruddock spoke to GRTV this week to reflect on events.
Missing so many starters, and up against a team fighting for their Premiership existence, Gloucester did what had to be done at Ashton Gate on Friday evening battling their way to a 32-14 Aviva Premiership win over Bristol Rugby.