Aussie stand-off McRae has missed the last four games after having a minor operation on his knee, and will partner Andy Gomarsall at half-back. The 30 year-old's last game was the away win at Cardiff Blues in round four of the tournament.
Number eight James Forrester also returns for his first start since the Blues clash in Cardiff, although the 23 year-old has seen action from the bench in the last four outings.
Adam Balding, who has been so impressive in recent weeks, makes way for Forrester, who this week was named in England's 42-man RBS Six Nations squad.
Gloucester go into Sunday's game knowing that they need to win with a try bonus point, prevent Stade Francais from getting any pool points, and score at least two tries and nine points more (or three tries more) than the French side on the day to qualify as pool winners.
Gloucester coach Dean Ryan said: "We have got to go out and be positive, and when we do that it tends to suit what we are trying to do as a team.
"We just hope we can get a bit of rhythm early on, get a lead, get the crowd behind us and build the pressure."
Gloucester:
15. Jon Goodridge
14. Marcel Garvey
13. Terry Fanolua
12. Henry Paul
11. James Bailey
10. Duncan McRae
9. Andy Gomarsall
1. Christo Bezuidenhout
2. James Parkes
3. Phil Vickery
4. Adam Eustace
5. Alex Brown
6. Jake Boer (c)
7. Andy Hazell
8. James Forrester
Replacements:
16. Rob Elloway, 17. Terry Sigley, 18. Mark Cornwell, 19. Peter Buxton, 20. Adam Balding, 21. Alex Page, 22. Nathan Mauger
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