Gloucester's Andy Hazell has been named in England starting line-up for Saturday's opening Six Nations clash against Wales in Cardiff.
The 26 year-old open-side is joined by Gloucester's Phil Vickery and James Forrester, who both start from the bench at the Millennium Stadium.
Andy Gomarsall and Henry Paul miss out on the matchday 22 and will return to Kingsholm training mid-week in time for Saturday's away clash at NEC Harlequins.
Hazell had picked up a knock to his knee against Worcester on Saturday, but the England medical team gave him the green light to continue training.
Elsewhere in the England line-up head coach Andy Robinson named 18 year-old Mathew Tait in his starting XV.
The talented youngster will start at outside centre alongside fellow Falcons centre Jamie Noon.
Robinson has selected Matt Dawson (London Wasps) for the scrum half position amidst stiff opposition from both Harry Ellis (Leicester Tigers) and Andy Gomarsall (Gloucester).
"Selection for the team to play Wales was very close indeed, with several players close to making the starting XV. Obviously injuries were also a factor in the selection process but I'm confident this is a strong team to face Wales on Saturday," said Robinson.
"I've never been afraid to select young talented players if I feel they are ready and Mathew Tait has demonstrated to me he has the form and speed to earn his place in the starting XV. I congratulate him on earning his first England cap. He will be playing alongside his clubmate Jamie Noon, which is something he will be familiar with.
"Selecting the scrum half position was a close call, however I have decided to start Matt Dawson who has shown great form for his club and can offer tremendous experience, with Harry Ellis on the bench. Andy Hazell impressed me during the autumn internationals at Twickenham and I feel he fully earns his place in the back row."
15 ROBINSON, Jason - Sale Sharks (Captain)
14 CUETO, Mark - Sale Sharks
13 TAIT, Mathew - Newcastle Falcons
12 NOON, Jamie - Newcastle Falcons
11 LEWSEY, Josh - London Wasps
10 HODGSON, Charlie - Sale Sharks
9 DAWSON, Matt -London Wasps
1 ROWNTREE, Graham - Leicester Tigers
2 THOMPSON, Steve - Northampton Saints
3 WHITE, Julian - Leicester Tigers
4 GREWCOCK, Danny - Bath
5 KAY, Ben - Leicester Tigers
6 MOODY, Lewis - Leicester Tigers
7 HAZELL, Andy - Gloucester
8 WORSLEY, Joe - London Wasps
16 TITTERRELL, Andy - Sale Sharks
17 VICKERY, Phil - Gloucester
18 BORTHWICK, Steve - Bath
19 FORRESTER, James - Gloucester
20 ELLIS, Harry - Leicester Tigers
21 BARKLEY, Olly - Bath
22 COHEN, Ben - Northampton Saints
Gloucester meet the Exeter Chiefs for the fourth time in competitive action this weekend, this time in the semi-final of the European Rugby Challenge Cup. Director of Rugby David Humphreys told the local media this week that this is the sort of game that Gloucester want to be involved in on a regular basis and that he and his team are looking forward to it.
Following the 29-26 loss to Harlequins, club captain Billy Twelvetrees spoke of his disappointment that the Cherry and Whites were unable to cash in on the home side's indiscipline and lose a lead on Saturday afternoon.
Number eight Gareth Evans admitted to a collective feeling of frustration as Gloucester lost narrowly at Harlequins on Saturday, but insisted that there are plenty of positives to draw upon ahead of next Saturday's European Rugby Challenge Cup semi-final at home to Exeter.
Gloucester travel to the Stoop on Saturday afternoon to take on Harlequins in the Aviva Premiership. The Cherry and Whites make just two changes from last weekend's win over Connacht as they seek consistency and continuity in their play as Nick Walshe told the local media this week.
Speaking to GRTV after the final whistle, Tom Palmer praised the Cherry and Whites concentration and desire to hold on to a narrow 14-7 victory. The second row topped the tackle charts with 19 as he led the home team's resistance.
Supporters who are still to purchase tickets for Saturday's European Rugby Challenge Cup semi-final at home to Exeter Chiefs at Kingsholm (kick off 7:45pm) are reminded that Early Bird prices are only valid until 6:30pm on Thursday evening.
The Gloucester Wheelchair Rugby team travelled to Fenton Manor Complex, Stoke on Trent last Saturday to take part in the final round of the GBWR Super Series of the season, knowing just one win would be enough to crown them Division 3 Champions.