Gloucester's Andy Hazell has been named in England starting line-up for Saturday's opening Six Nations clash against Wales in Cardiff.
The 26 year-old open-side is joined by Gloucester's Phil Vickery and James Forrester, who both start from the bench at the Millennium Stadium.
Andy Gomarsall and Henry Paul miss out on the matchday 22 and will return to Kingsholm training mid-week in time for Saturday's away clash at NEC Harlequins.
Hazell had picked up a knock to his knee against Worcester on Saturday, but the England medical team gave him the green light to continue training.
Elsewhere in the England line-up head coach Andy Robinson named 18 year-old Mathew Tait in his starting XV.
The talented youngster will start at outside centre alongside fellow Falcons centre Jamie Noon.
Robinson has selected Matt Dawson (London Wasps) for the scrum half position amidst stiff opposition from both Harry Ellis (Leicester Tigers) and Andy Gomarsall (Gloucester).
"Selection for the team to play Wales was very close indeed, with several players close to making the starting XV. Obviously injuries were also a factor in the selection process but I'm confident this is a strong team to face Wales on Saturday," said Robinson.
"I've never been afraid to select young talented players if I feel they are ready and Mathew Tait has demonstrated to me he has the form and speed to earn his place in the starting XV. I congratulate him on earning his first England cap. He will be playing alongside his clubmate Jamie Noon, which is something he will be familiar with.
"Selecting the scrum half position was a close call, however I have decided to start Matt Dawson who has shown great form for his club and can offer tremendous experience, with Harry Ellis on the bench. Andy Hazell impressed me during the autumn internationals at Twickenham and I feel he fully earns his place in the back row."
15 ROBINSON, Jason - Sale Sharks (Captain)
14 CUETO, Mark - Sale Sharks
13 TAIT, Mathew - Newcastle Falcons
12 NOON, Jamie - Newcastle Falcons
11 LEWSEY, Josh - London Wasps
10 HODGSON, Charlie - Sale Sharks
9 DAWSON, Matt -London Wasps
1 ROWNTREE, Graham - Leicester Tigers
2 THOMPSON, Steve - Northampton Saints
3 WHITE, Julian - Leicester Tigers
4 GREWCOCK, Danny - Bath
5 KAY, Ben - Leicester Tigers
6 MOODY, Lewis - Leicester Tigers
7 HAZELL, Andy - Gloucester
8 WORSLEY, Joe - London Wasps
16 TITTERRELL, Andy - Sale Sharks
17 VICKERY, Phil - Gloucester
18 BORTHWICK, Steve - Bath
19 FORRESTER, James - Gloucester
20 ELLIS, Harry - Leicester Tigers
21 BARKLEY, Olly - Bath
22 COHEN, Ben - Northampton Saints
As Gloucester prepare for their 39th game of the season, against Bordeaux-Begles at Sixways on Sunday, David Humphreys told the local media that this week has been all about getting the players mentally and physically ready after a tough game against Connacht last Sunday.
Speaking to GRTV after the 40-32 victory over Connacht on Sunday, skipper Billy Twelvetrees explained that Gloucester had had to learn to be patient and cut out the errors to earn the win and progress to next weekend's final play-off against Bordeaux-Begles.
Jonny May's superb late score capped a thrilling 40-32 European play-off win over Connacht on Sunday. The winger spoke afterwards of his team's character and spirit as he looked ahead to one more week of rugby.
Speaking to GRTV this afternoon, Director of Rugby David Humphreys hailed the 'never say die' attitude of the team, after despite not being at their best, fighting back to take a 40-32 win after extra time over Connacht.
Jonny May continues on the wing on Sunday as Connacht come to town, and the England wing explains to the local media this week that he is delighted with his form and is looking forward to taking on Pat Lam's men.
Speaking to Russ Hargreaves of Talking Rugby at Friday's launch of the Aviva Premiership Rugby and Singha 7s fixtures, Henry Trinder discussed the early stages of preseason and the campaign that lies ahead.
Premiership Rugby have this morning confirmed the order of fixtures for the 2015/16 season, and Gloucester Rugby will start their campaign at Kingston Park, taking on Newcastle Falcons on Friday 16 October, 19:45.