Gloucester's Andy Hazell has been named in England starting line-up for Saturday's opening Six Nations clash against Wales in Cardiff.
The 26 year-old open-side is joined by Gloucester's Phil Vickery and James Forrester, who both start from the bench at the Millennium Stadium.
Andy Gomarsall and Henry Paul miss out on the matchday 22 and will return to Kingsholm training mid-week in time for Saturday's away clash at NEC Harlequins.
Hazell had picked up a knock to his knee against Worcester on Saturday, but the England medical team gave him the green light to continue training.
Elsewhere in the England line-up head coach Andy Robinson named 18 year-old Mathew Tait in his starting XV.
The talented youngster will start at outside centre alongside fellow Falcons centre Jamie Noon.
Robinson has selected Matt Dawson (London Wasps) for the scrum half position amidst stiff opposition from both Harry Ellis (Leicester Tigers) and Andy Gomarsall (Gloucester).
"Selection for the team to play Wales was very close indeed, with several players close to making the starting XV. Obviously injuries were also a factor in the selection process but I'm confident this is a strong team to face Wales on Saturday," said Robinson.
"I've never been afraid to select young talented players if I feel they are ready and Mathew Tait has demonstrated to me he has the form and speed to earn his place in the starting XV. I congratulate him on earning his first England cap. He will be playing alongside his clubmate Jamie Noon, which is something he will be familiar with.
"Selecting the scrum half position was a close call, however I have decided to start Matt Dawson who has shown great form for his club and can offer tremendous experience, with Harry Ellis on the bench. Andy Hazell impressed me during the autumn internationals at Twickenham and I feel he fully earns his place in the back row."
15 ROBINSON, Jason - Sale Sharks (Captain)
14 CUETO, Mark - Sale Sharks
13 TAIT, Mathew - Newcastle Falcons
12 NOON, Jamie - Newcastle Falcons
11 LEWSEY, Josh - London Wasps
10 HODGSON, Charlie - Sale Sharks
9 DAWSON, Matt -London Wasps
1 ROWNTREE, Graham - Leicester Tigers
2 THOMPSON, Steve - Northampton Saints
3 WHITE, Julian - Leicester Tigers
4 GREWCOCK, Danny - Bath
5 KAY, Ben - Leicester Tigers
6 MOODY, Lewis - Leicester Tigers
7 HAZELL, Andy - Gloucester
8 WORSLEY, Joe - London Wasps
16 TITTERRELL, Andy - Sale Sharks
17 VICKERY, Phil - Gloucester
18 BORTHWICK, Steve - Bath
19 FORRESTER, James - Gloucester
20 ELLIS, Harry - Leicester Tigers
21 BARKLEY, Olly - Bath
22 COHEN, Ben - Northampton Saints
Speaking to the media following the 31-33 West Country Challenge Cup defeat to Exeter Chiefs at the Memorial Stadium, Director of Rugby David Humphreys was full of praise for his side's battling qualities in a bruising encounter but concerned about the injuries picked up.
The West Country Challenge Cup fixture against the Exeter Chiefs at the Memorial Stadium in Bristol on Saturday (kick off 3pm) will be Gloucester's last chance to work on things like new combinations says Director of Rugby, David Humphreys.
Speaking after the 30-21 West Country Challenge Cup defeat at Bath, Director of Rugby David Humphreys spoke of the improvements his team are making as preseason progresses but acknowledges that there is still work to do ahead of the start of the Aviva Premiership.
Speaking to the local media ahead of Saturday's trip to Bath Rugby in the West Country Challenge Cup, front rower Nick Wood spoke of the hard work put in across the extended preseason and highlighted the competition for front row spots in the squad.
Gloucester have named a 30 man squad for the latest round of West Country Challenge Cup action against Bath on Saturday, with Director of Rugby David Humphreys stressing the need to keep an eye on player workload ahead of what will be a long, tough season.
Describing the 50-7 West Country Challenge Cup win over Bath on Sunday as a '...good hit out...', wing Charlie Sharples admitted that it had been a good opportunity to put into practice things that the squad have been trying out in training in recent weeks.
Speaking to the local media after the 50-7 victory over Bath Rugby on Sunday, David Humphreys was happy with his squad's effort, with the most important aspect being the game time earned by his players.
Gloucester make wholesale changes to the side that started at Exeter last Saturday as they prepare to take on Bath at the Memorial Stadium, Bristol on Sunday in the West Country Challenge Cup (kick off 3pm). The Director of Rugby told GRTV that the players are raring to go and that he's looking forward to seeing different combinations in action.
Following on from the success of the Fanzone in Gloucester, Kingsholm is opening its gates to rugby fans for the final games of Rugby World Cup 2015. Catch the rest of the games throughout the tournament for free on the big screen at Kingsholm Stadium and also get a chance to see the first team training on Sunday.
To celebrate being a Rugby World Cup match venue, Gloucester Rugby is proud to launch The Gloucester Burger, distinctly different to any other, made entirely from locally farmed Pedigree Gloucester Cattle, the UK's rarest breed.