Gloucester's Andy Hazell has been named in England starting line-up for Saturday's opening Six Nations clash against Wales in Cardiff.
The 26 year-old open-side is joined by Gloucester's Phil Vickery and James Forrester, who both start from the bench at the Millennium Stadium.
Andy Gomarsall and Henry Paul miss out on the matchday 22 and will return to Kingsholm training mid-week in time for Saturday's away clash at NEC Harlequins.
Hazell had picked up a knock to his knee against Worcester on Saturday, but the England medical team gave him the green light to continue training.
Elsewhere in the England line-up head coach Andy Robinson named 18 year-old Mathew Tait in his starting XV.
The talented youngster will start at outside centre alongside fellow Falcons centre Jamie Noon.
Robinson has selected Matt Dawson (London Wasps) for the scrum half position amidst stiff opposition from both Harry Ellis (Leicester Tigers) and Andy Gomarsall (Gloucester).
"Selection for the team to play Wales was very close indeed, with several players close to making the starting XV. Obviously injuries were also a factor in the selection process but I'm confident this is a strong team to face Wales on Saturday," said Robinson.
"I've never been afraid to select young talented players if I feel they are ready and Mathew Tait has demonstrated to me he has the form and speed to earn his place in the starting XV. I congratulate him on earning his first England cap. He will be playing alongside his clubmate Jamie Noon, which is something he will be familiar with.
"Selecting the scrum half position was a close call, however I have decided to start Matt Dawson who has shown great form for his club and can offer tremendous experience, with Harry Ellis on the bench. Andy Hazell impressed me during the autumn internationals at Twickenham and I feel he fully earns his place in the back row."
15 ROBINSON, Jason - Sale Sharks (Captain)
14 CUETO, Mark - Sale Sharks
13 TAIT, Mathew - Newcastle Falcons
12 NOON, Jamie - Newcastle Falcons
11 LEWSEY, Josh - London Wasps
10 HODGSON, Charlie - Sale Sharks
9 DAWSON, Matt -London Wasps
1 ROWNTREE, Graham - Leicester Tigers
2 THOMPSON, Steve - Northampton Saints
3 WHITE, Julian - Leicester Tigers
4 GREWCOCK, Danny - Bath
5 KAY, Ben - Leicester Tigers
6 MOODY, Lewis - Leicester Tigers
7 HAZELL, Andy - Gloucester
8 WORSLEY, Joe - London Wasps
16 TITTERRELL, Andy - Sale Sharks
17 VICKERY, Phil - Gloucester
18 BORTHWICK, Steve - Bath
19 FORRESTER, James - Gloucester
20 ELLIS, Harry - Leicester Tigers
21 BARKLEY, Olly - Bath
22 COHEN, Ben - Northampton Saints
Speaking to the local media this week, Richard Hibbard expressed his excitement ahead of the West Country derby and that there is an extra spring in the step of the Cherry and Whites ahead of the tough challenge.
With such a short turnaround between the two games, and Gloucester looking to reintegrate several players into the line-up after the Autumn international series, Tom Savage told GRTV that the Cherry and Whites will keep changes to a minimum for the European Rugby Challenge Cup game in Zebre on Saturday.
Gloucester travel to Italy this weekend to take on Zebre in Round Four of the European Rugby Challenge Cup. The Cherry and Whites defeated the Italian side 35-10 last Sunday, but Director of Rugby David Humphreys is looking for an improved performance in the return fixture.
On a tough evening at Kingsholm, Gloucester could escape neither a suffocating Bath defence, nor the whistle of referee Greg Garner as six penalties and a penalty try paved the way to a 39-16 win for the visitors.
Gloucester Rugby welcome Sione Kalamafoni, Greig Laidlaw and Tom Palmer back to the starting line up and feature David Halaifonua in a matchday squad for the first time, as they resume Aviva Premiership action against Bath Rugby at Kingsholm on Saturday (kick off 5:30pm).