Nigel Melville makes four changes to the Gloucester starting line-up for Saturday's 13,000 capacity Powergen Cup quarter-final against Bristol Shoguns at Kingsholm (kick off 2.45pm).
Loose-head prop Terry Sigley and Welsh international hooker Mefin Davies come into the front row alongside Phil Vickery. Both James Parkes and Christo Bezuidenhout move to the bench.
32 year-old Davies missed the last two European games as he signed for Gloucester after the Heineken Cup registration deadline.
Adam Balding starts at number eight in place of James Forrester, and Seti Kiole comes in on the left wing after James Simpson-Daniel was ruled out earlier in the week.
Jon Goodridge and Marcel Garvey continue a superb sequence of appearances that has seen both of them start every single one of Gloucester's 21 games (including this weekend) this season.
Mark Foster comes on to the bench, alongside Nathan Mauger and Alex Page as cover for the backs.
The game is a 13,000 sell-out and tickets sold out two weeks ago. The game will be shown live on BBC1 in the West and West Midlands regions. Supporters outside of these two regions can also watch the match through Sky digital.
15. Jon Goodridge
14. Marcel Garvey
13. Terry Fanolua
12. Henry Paul
11. Seti Kiole
10. Duncan McRae
9. Andy Gomarsall
1. Terry Sigley
2. Mefin Davies
3. Phil Vickery
4. Adam Eustace
5. Alex Brown
6. Jake Boer (c)
7. Andy Hazell
8. Adam Balding
16. James Parkes, 17. Christo Bezuidenhout, 18. Peter Buxton, 19. James Forrester, 20. Alex Page, 21. Nathan Mauger, 22. Mark Foster
Willi Heinz scored Gloucester's second try as the Cherry and Whites overturned a disappointing first 40 minutes and 0-6 half time deficit, to earn a 26-18 Aviva Premiership victory over Bristol Rugby on Saturday.
It's the first Gloucester-Bristol derby at Kingsholm in over eight years this Saturday (kick off 4:30pm) and, previewing the game with the local media this week, Defence Coach Jonny Bell stressed that, with both teams in the bottom half of the table, they both need the points.
Speaking to the local media this week, Gloucester front rower John Afoa knows the challenge ahead this week against Bristol, and calls on the Cherry and Whites to make the most of home advantage as a determined squad look to bounce back from a narrow loss to Saracens.
Tom Savage speaks to GRTV and the local media as Gloucester went down by 24-20 at Saracens on Sunday afternoon. The second row was disappointed with the result, despite a strong showing from the hosts.
Speaking immediately after the game, skipper Willi Heinz thought that Gloucester had executed their game plan reasonably well and competed hard against Saracens. However, it wasn't enough but the squad will have plenty to work on this week ahead of the derby match against Bristol.
Gloucester may be coming off their best win of the season, the 38-16 victory over Wasps last weekend, but Director of Rugby David Humphreys admits that Sunday's trip to Saracens is an even tougher test.
Looking to try a new sport? Look no further than Walking Rugby as thanks to Gloucester Rugby you can come along and try out the fast-growing sport at taster sessions across the county, starting this Wednesday.
Gloucester return to European Rugby Challenge Cup action on Thursday evening with the visit of Stade Rochelais to Kingsholm (kick off 7:45pm). Early Bird ticket prices are available until 6:30pm on matchday.
Talk about a game of two halves. Things looked grim on Saturday as Gloucester trailed 0-6 to Bristol at half-time. However, Matt Scott's eighth try of the season got Gloucester off and running, and the visitors fell apart as the Cherry and Whites eased to a 26-18 bonus point Aviva Premiership win.