Hazell, who has been missing since a knock during the London Irish game at the end of March, is the one change to the forwards pack from the team's last Premiership outing away at Sale Sharks.
19 year-old England U21 international Olly Morgan makes his first start for Gloucester on the wing after two replacement appearances in the last month.
Morgan is joined on the wing by James Bailey, with both Seti Kiole (shoulder) and Marcel Garvey (elbow) out injured.
Terry Fanolua returns at centre after missing the last two games with a back injury, and Duncan McRae also starts at fly-half after being on the bench against the Sharks two weeks ago.
Jon Goodridge completes the milestone of starting every competitive fixture for Gloucester this season. The 24 year-old full-back has missed only nine minutes of Premiership action throughout the entire league campaign, being replaced after 78 minutes against Wasps and after 73 minutes against Northampton.
As well as Garvey and Kiole's injuries, prop Phil Vickery also misses out, as he continues his recovery from a broken arm. Other players missing through injury include Mark Cornwell (neck), Chris Fortey (ankle), James Parkes (wrist) and Henry Paul (knee).
Gloucester can't finish any higher than sixth, or any lower than seventh in the Premiership. A win against Saracens would guarantee sixth place, and depending on how results go elsewhere could mean a home Wild Card semi-final the following weekend.
Gloucester:
15. Jon Goodridge
14. James Bailey
13. James Simpson-Daniel
12. Terry Fanolua
11. Olly Morgan
10. Duncan McRae
9. Andy Gomarsall
1. Nick Wood
2. Mefin Davies
3. Gary Powell
4. Adam Eustace
5. Alex Brown
6. Jake Boer
7. Andy Hazell
8. Adam Balding (c)
Replacements:
16. Olivier Azam
17. Terry Sigley
18. Peter Buxton
19. James Forrester
20. Alex Page
21. Brad Davies
22. Simon Amor/Mark Foster
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