Gloucester make a number of changes to the starting line-up for Friday's Zurich Premiership clash at Sale.
Andy Hazell (head), Phil Vickery (arm), Marcel Garvey (elbow) and Terry Fanolua (back) are all missing, along with long term injured Henry Paul (knee), Chris Fortey (ankle) and Mark Cornwell (neck).
Mark Foster starts on the wing in place of Marcel Garvey, who injured his elbow against Leeds. The 21 year-old started at inside centre against the Tykes last weekend, and completes a back three of Seti Kiole and Jon Goodridge for the game at the Sharks.
Nathan Mauger comes in to the centres to partner James Simpson-Daniel, with Terry Fanolua still ruled out with a back injury.
Former England U21 fly-half Brad Davies partners Andy Gomarsall at half-back, with Duncan McRae starting from the bench (Gloucester have two overseas players - McRae and Mauger - and regulations state only one can be on the field at one time).
Nick Wood returns to the side in the front row alongside Mefin Davies and Gary Powell, and Adam Eustace and Alex Brown continuing in the second row.
Andy Hazell hasn't recovered from the knock to the head he took in the win over London Irish three weeks ago, and Academy product Luke Narraway wears the number seven shirt. Jake Boer moves from open-side to blind-side.
Captain Adam Balding is also back after missing last weekend against Leeds, with Peter Buxton and James Forrester named on the bench.
The replacements bench is completed with Olivier Azam, Terry Sigley, Alex Page, Duncan McRae and Olly Morgan.
15. Jon Goodridge
14. Mark Foster
13. James Simpson-Daniel
12. Nathan Mauger
11. Seti Kiole
10. Brad Davies
9. Andy Gomarsall
1. Nick Wood
2. Mefin Davies
3. Gary Powell
4. Adam Eustace
5. Alex Brown
6. Jake Boer
7. Luke Narraway
8. Adam Balding (c)
16. Olivier Azam
17. Terry Sigley
18. Peter Buxton
19. James Forrester
20. Alex Page
21. Duncan McRae
22. Olly Morgan
Speaking to GRTV after the game, Director of Rugby David Humphreys spoke of his delight in securing a 28-6 win over Harlequins at Kingsholm. He hailed the home side's defence which they were quick to turn into attack.
Speaking to the local media, Bill Meakes this week explained how he was relishing the challenge against Harlequins at Kingsholm, and that he is enjoying the opportunity to develop his game time, and repaying the faith from the Cherry and White coaches
Gloucester look to build upon the local derby win over Bath last weekend with Harlequins the visitors to Kingsholm on Saturday (kick off 3pm). Director of Rugby David Humphreys is expecting a close game with the two teams well matched, although it may not be a 78 point thriller like the last time the two teams met.
Named Man of the Match by BT Sport, scrum-half Willi Heinz said after the 15-11 win at Bath on Friday evening that it was a pretty happy Gloucester dressing room and reward for a lot of hard work put in during the week leading up to the game.
Speaking after the 15-11 win over Bath at the Rec on Friday evening, David Humphreys heaped praise on his players, pointing out how they had bounced back after last week's tough defeat to overcome a rough start before controlling the game and earning the win.
Gloucester Rugby hooker Richard Hibbard spoke to the local media this week as the Cherry and Whites prepare to face Bath Rugby in the Aviva Premiership. The Welshman is ready to bounce back at The Rec.
Speaking to the local media about the local derby against Bath at the Rec on Friday evening, Director of Rugby David Humphreys acknowledged that it will be a tough encounter but hugely exciting at the same time and one the squad are looking forward to.
A visibly disappointed Billy Twelvetrees admitted that it was a very sombre Gloucester dressing room as a last minute try and conversion condemned the Cherry and Whites to an 18-19 defeat against Leicester Tigers on Saturday.
After a disappointing opening weekend loss to their Scottish counterparts, England U20s will be eager to bounce back in Italy this evening, with Gloucester flyer Mat Protheroe set to pull the strings from fly half.
Gloucester Rugby make just the one change to the starting line up that won at Bath last Friday evening, flanker Matt Kvesic restored to the starting XV as the Cherry and Whites welcome Harlequins to Kingsholm in the Aviva Premiership on Saturday (kick off 3pm).
The Early Bird deadline for ticket purchases for the Aviva Premiership fixture against Harlequins on Saturday will expire at 6:30pm on Thursday evening, with tickets already limited for one area of Kingsholm.