GLOUCESTER will monitor the fitness of lock Alex Brown over the next seven days after he was ruled out of European Challenge Cup action with a neck injury.
The Kingsholm forward has been diagnosed with a disc problem that will be assessed over the next week.
He will not travel with the Gloucester side to Bayonne for their opening Challenge Cup game this Saturday. Head coach Dean Ryan said: "Alex has a disc problem and he will be spending the next seven days being assessed. Hopefully after that time we will get some positive news."
Brown has been one of Gloucester's stand-out players this season and has made 108 Premiership appearances with five tries.
"It's disappointing that the injury has happened at this stage but I will work hard with the medical team over the next week and aim to resume playing as soon as possible," Brown said.
Speaking to the local media on Thursday, Matt Kvesic was looking forward to the trip to Newcastle Falcons, and the captain is looking to lead from the front with plenty for the Cherry and Whites to work on.
Gloucester saw a 12-0 lead overturned by Harlequins on Friday night as the visitors ran out 22-15 winners. After the game, Director of Rugby David Humphreys spoke about missed opportunities on the night.
Speaking to the local media on Thursday, James Hudson explained his excitement for tonight's game with Harlequins and that he is backing the Cherry and White squad to impress during the next set of Aviva Premiership games.
20 year old Lewis Ludlow was one of Gloucester's young guns who contributed hugely to the 18-9 LV= Cup win at London Welsh on Sunday afternoon. After the game, he praised his team mates for the massive team effort by an inexperienced side.
There are three changes to Gloucester Rugby's starting line-up for Friday evening's Aviva Premiership fixture away at Newcastle Falcons. Steve McColl will make his first Premiership start for the club.