Nigel Melville has parted company from Gloucester Rugby Club with immediate effect after just over three seasons in the role as director of rugby.
Gloucester chairman Tom Walkinshaw said: "On behalf of everyone at the Club and the supporters I would like to thank Nigel for his work at Gloucester Rugby Club, and wish him all the best for the future.
"He was part of this club on one of our most memorable days, when we won the Powergen Cup at Twickenham, and I know that moment will be an ever-lasting memory for everyone."
Melville took over from Philippe Saint Andre at the Kingsholm club in the Spring of 2002, and saw his Gloucester side defeat Bristol Shoguns in that season's Zurich Championship final.
The West Country club recruited Dean Ryan as coach to join Melville in the summer of 2002, and Gloucester went on to finish top of the table during the regular Zurich Premiership season at the end of 2003 and win the Powergen Cup, before losing the Zurich Premiership final to Wasps at Twickenham.
Gloucester have finished fourth and sixth respectively in the last two seasons, and last weekend missed out on next season's Heineken Cup after losing to Saracens in the Zurich Wild Card final.
Nigel Melville said: "I'd like to thank everyone from the players, to the staff at the club and the supporters for their time and support over the last few seasons. Gloucester is a special club and there's been some great times since I arrived. I wish everyone all the best."
The Gloucester players are currently on their summer break, with pre-season activities due to start at the end of June. Team affairs will be managed by coach Dean Ryan in an interim capacity.
Gloucester's board of directors will not be making any further comment at the current time, and will take the next few weeks to consider the playing structure at the Club.
Everyone at Gloucester Rugby Club would like to wish Nigel Melville all the best for the future.
Speaking to the local media this week, back row flanker Jacob Rowan said that he is excited for the challenge at the Ricoh Arena this Sunday, and added that the players know the responsibility is theirs to deliver against the league leaders.
Ben Morgan was on media duty this week, and as Gloucester prepare for Sunday's trip to Wasps, the number eight is looking forward to see Gloucester go toe-to-toe with another of the Aviva Premiership's front runners.
Tom Marshall scored his first Gloucester try in the 31-23 win over Saracens on Friday evening and was named Man of the Match. Talking to GRTV, he praised the forwards for setting the tone on the night.
Matt Scott was on media duty this week, and the Scottish international spoke about the benefit of having a full week of training with his club mates and the determination to get back to performing well against Saracens this Friday evening.
After the disappointment of last weekend's performance at Leicester, Director of Rugby David Humphreys told GRTV that he expects a big response from Gloucester in Friday's Aviva Premiership fixture at home to Saracens (kick off 7:45pm).
Gloucester battled bravely against Wasps on Sunday, but it was a case of taking chances at the Ricoh Arena. Gloucester didn't make the most of theirs while Wasps did, and that proved to be the difference.
Gloucester were competitive for long periods at the Ricoh Arena on Sunday afternoon, but were left to rue a host of missed scoring opportunities throughout as Wasps hit back to earn a 35-22 Aviva Premiership win.
Gloucester's Ciaran Knight made his first start at tighthead prop, Henry Walker made his first appearance as a second half replacement and Alex Seville also featured as England U20s might it three from three in the U20s Six Nations with a 46-0 win over Italy in Darlington on Friday night.