Luke Narraway comes into the back row for Gloucester's Zurich Wild Card semi-final against Newcastle at Kingsholm on Sunday (Sun 8 May, Kingsholm, kick off 3.15pm - Tickets AVAILABLE).
The 21 year-old flanker replaces the injured Andy Hazell, who misses out after taking a knock to the head against Saracens last weekend.
Narraway started Gloucester's last clash with the Falcons at the end of February at Kingston Park and scored the team's fourth try in the 27-27 draw.
Seti Kiole returns to the wing after missing last Saturday's game through injury. He joins a reshuffled back three.
Jon Goodridge misses his first competitive fixture of the season with a shoulder injury that saw him go off after half an hour against Saracens, and Marcel Garvey is still absent with an elbow injury.
19 year-old England U21 Olly Morgan starts at full-back, with James Bailey staying on the wing after an impressive performance in last week's final league clash.
Director of rugby Nigel Melville and coach Dean Ryan have the final team run through on Saturday morning, when a few of the players will look to come through after a number of niggles caused disruption this week.
Jon Goodridge and Marcel Garvey are joined on the sidelines by Phil Vickery (broken arm), Mark Cornwell (neck), Chris Fortey (ankle), James Parkes (wrist) and Henry Paul (knee).
More than 5,200 tickets have been sold for the Wild Card semi-final, and supporters have until 5pm on Friday to take advantage of the 'early bird' discount. Tickets are available on-line at www.gloucesterrugbyclub.com, from the ticket hotline on 0871 871 8781 and from the ticket office at the ground.
Gloucester: 15. Olly Morgan
14. James Bailey
13. James Simpson-Daniel
12. Terry Fanolua
11. Seti Kiole
10. Duncan McRae
9. Andy Gomarsall
1. Nick Wood
2. Mefin Davies
3. Gary Powell
4. Adam Eustace
5. Alex Brown
6. Jake Boer
7. Luke Narraway
8. Adam Balding (c)
16. Olivier Azam
17. Terry Sigley
18. Peter Buxton
19. James Forrester
20. Alex Page
21. Brad Davies
22. Mark Foster
Tom Marshall scored his first Gloucester try in the 31-23 win over Saracens on Friday evening and was named Man of the Match. Talking to GRTV, he praised the forwards for setting the tone on the night.
Matt Scott was on media duty this week, and the Scottish international spoke about the benefit of having a full week of training with his club mates and the determination to get back to performing well against Saracens this Friday evening.
After the disappointment of last weekend's performance at Leicester, Director of Rugby David Humphreys told GRTV that he expects a big response from Gloucester in Friday's Aviva Premiership fixture at home to Saracens (kick off 7:45pm).
Gloucester travel to Tigers this Saturday in good spirits, and fly half Billy Burns is looking forward to testing himself in one of the toughest environments in the league as the Cherry and White hunt vital points as attention returns to the Aviva Premiership
After a good run of recent results, Gloucester will travel to take on Leicester in a good frame of mind according to Director of Rugby David Humphreys, but are well aware of the challenge that lies in wait.
Gloucester Rugby continues to strengthen its commitment to working across Gloucestershire and the surrounding area and is looking to recruit an enthusiastic, motivated and dedicated individual to the role of Wheelchair Rugby Coach
Wales have named their side to face Scotland at Murrayfield on Saturday. They make just one change as George North returns in place of Alex Cuthbert and Gloucester's Ross Moriarty starts again at number eight.
Sunday saw Gloucester Rugby host the Land Rover Cup at Dean Close School in Cheltenham, and it was Tewkesbury and Old Pats who will represent the club at Twickenham in the U11s and U12s categories respectively.