MIKE TINDALL underwent surgery on Saturday evening to have a pin inserted into the lower third of the tibia in his right leg following his fracture against Newcastle Falcons on Friday.
The Gloucester and England star suffered the undisplaced fracture in the second half of Gloucester's 19-12 defeat at Kingston Park and faces a minimum of 12 weeks' recovery time.
"An injury of this severity to one of our key individuals at this stage of the season is obviously a serious blow because Mike possesses all the characteristics you require during the play-offs," head coach Dean Ryan told www.gloucesterrugby.co.uk
"He has big-game experience, natural leadership qualities and knows what it takes to win these one-off matches and we will miss his contribution."
Gloucester can also confirm that Karl Pryce faces a lengthy spell on the sidelines. The former rugby league winger re-fractured a bone in his left foot during his Guinness Premiership debut against Northampton last month and has had a pin inserted.
The 20-year-old will now focus on rehabilitation over the summer with a view to returning to first team action at the start of next season.
"We wish Mike and Karl all the very best in their recovery processes and will be right behind them," added Ryan.
Speaking with the local media before the Gloucester team set off on the long trip north to Newcastle, Director of Rugby David Humphreys discussed his team selection and stated that Friday night's meeting will be a challenging one.
Speaking to the local media on Thursday, Matt Kvesic was looking forward to the trip to Newcastle Falcons, and the captain is looking to lead from the front with plenty for the Cherry and Whites to work on.
Gloucester saw a 12-0 lead overturned by Harlequins on Friday night as the visitors ran out 22-15 winners. After the game, Director of Rugby David Humphreys spoke about missed opportunities on the night.
Speaking to the local media on Thursday, James Hudson explained his excitement for tonight's game with Harlequins and that he is backing the Cherry and White squad to impress during the next set of Aviva Premiership games.
After the huge success of the Darts evening in March, Gloucester Rugby and events sponsors Worthington's are pleased to present an evening with Darts Legends Eric Bristow, Keith Deller, Bobby George and Wayne Mardle hosted by Russ Bray on Tuesday 9 December.
In a unique collaboration, the West's big three rugby rivals -Bristol Rugby, Bath Rugby and Gloucester Rugby - have joined forces to launch 'Break The Cycle' for 2015, and it's bigger and better than ever before.