HOOKER Andy Titterrell will make his first Guinness Premiership start for Gloucester against Saracens on Sunday (3pm).
The former Sale man will be joined in the front row by Nick Wood as head coach Dean Ryan shuffles his forward pack for Gloucester's second successive away game.
Wood did not feature during Gloucester's 49-24 victory over Leeds Carnegie last Sunday but comes in for Patrice Collazo, while Titterrell starts in place of Olivier Azam, who moves to the bench.
"I don't think it's hard to make changes in this squad," said head coach Ryan. "We recognise the group is more than 15 players and the quality of the group is more than 15 players which is very important to us.
"The season is nine months long we will make changes which aren't necessarily on selection and form but are when there are people as good to come into the position.
"It's important to keep people hungry and keep pressure on - I thought Andy was very impressive when he came off the bench last weekend and we know of Nick's qualities as an emerging prop who was good enough to earn selection to an England squad last season.
"We have picked a team we feel is right for this game and this environment and we are happy with the options."
The only other change is in the second row where Peter Buxton replaces Jonathan Pendlebury at number four meaning Alasdair Strokosch comes in on the flank.
"As a group I think we appreciate what was on offer last weekend will not be there on Sunday and I think Alan Gaffney [Saracens' director of rugby] deserves a lot of credit for what he has already achieved there.
"They play at high speed, will try and create pressure and have a very good group of players. This will be a significant away game for us."
Wood and Titterrell will be joined in the front row with Carlos Nieto, while Buxton will partner Alex Brown at lock. Strokosch comes in on the blindside flank and will partner Andy Hazell and Luke Narraway at number eight.
The backs remain the same which means Lesley Vainikolo, who scored a debut record five tries against Leeds, will play his second Premiership match in a back three alongside James Simpson-Daniel and Iain Balshaw.
Leon Lloyd and Anthony Allen are the centre combination with Ryan Lamb and Mike Prendergast at half-back.
On the bench, Adam Balding returns to the squad in place of Dan Tuohy and Pendlebury makes a straight swap with Strokosch. Azam and Christian Califano are the front row replacements.
Scrum-half Dave Lewis, utility back Willie Walker and full-back Olly Morgan are the three-quarter options. Walker returns after suffered a dead leg in last Friday's team run. Please note that James Bailey is travelling with the squad.
GLOUCESTER (v Saracens, Sunday, September 23 3pm): Iain Balshaw; James Simpson-Daniel, Leon Lloyd, Anthony Allen, Lesley Vainikolo; Ryan Lamb, Mike Prendergast; Nick Wood, Andy Titterrell, Carlos Nieto, Peter Buxton (capt), Alex Brown, Alasdair Strokosch, Andy Hazell, Luke Narraway. Reps: Olivier Azam, Christian Califano, Jonathan Pendlebury, Adam Balding, Dave Lewis, Willie Walker, Olly Morgan.
Speaking to GRTV after the 40-29 Aviva A League win over Wasps Rugby, Academy Coach Rich Whiffin explained his pride in the squad to overcome a strong opponent and book their spot in next week's Aviva A League final.
Willi Heinz returned from injury to skipper Gloucester to a famous 16-14 win over Stade Rochelais on Saturday evening. Speaking after the game in France, Heinz admitted the win wasn't pretty but was full of courage and a great result for the club.
Billy Burns contributed all Gloucester's points in the 16-14 European Rugby Challenge Cup win in La Rochelle on Saturday evening, but dedicated the victory to the whole squad whilst also praising the travelling support.
Speaking after Gloucester's brave 16-14 win against Stade Rochelais which clinches a European Rugby Challenge Cup final spot, Director of Rugby David Humphreys paid tribute to the way the team had executed the game plan in a hostile environment against quality opposition.
Greig Laidlaw returns to the Gloucester Rugby squad this week, and his inclusion is an important one after a serious ankle injury. The Scottish scrum half is determined to drive the team forward in their European Rugby Challenge Cup semi final in La Rochelle this Saturday.
Gloucester take on La Rochelle in the European Rugby Challenge Cup semi-final in France on Saturday evening, with the Top 14 side the favourites in the eyes of the bookmakers. However, David Humphreys is looking for his side to rise to the occasion against a familiar opponent.
Speaking to GRTV after Saturday's 39-30 Aviva Premiership win over Sale, Mark Atkinson admitted that the performance wasn't perfect but that the team's character shone through in a game that could easily have slipped away.
Scotland scrum-half Greig Laidlaw is targeting a 'unique' finish to his Gloucester tenure in the European Rugby Challenge Cup final at the venue where his professional playing career began, BT Murrayfield Stadium (Friday 12 May).
Gloucester's young United side once again dug deep to take an illustrious scalp, overturning a half-time deficit to earn a 40-29 victory over Wasps and earn a place in the Aviva Premiership A League final.