ENGLAND international Olly Morgan will wear the number 15 shirt for Gloucester's pivotal Heineken Cup match against Bourgoin tomorrow.
Iain Balshaw moves to the wing to cover the absence of Lesley Vainikolo, who has returned to New Zealand for a week because of a family bereavement.
"Our thoughts are with Lesley and his family at this time and the club will give him all the support he needs before he returns to the first team squad," said head coach Dean Ryan.
"Family is very much central to Lesley's life and for that reason we respect his wishes to be with them at this time and want his privacy to be maintained. We will not be making any further comment until he returns."
The rest of Ryan's line-up remains virtually intact from the one that has seen Gloucester establish a narrow lead in Pool Two - although he is without second row Marco Bortolami (calf) and breakaway flanker Andy Hazell (twisted knee).
Mike Tindall and Anthony Allen will resume their centre partnership having missed the EDF Energy Cup victory over the Dragons and James Simpson-Daniel returns to the wing.
Ryan Lamb is partnered by Rory Lawson at half-back.
"We need to combine experience with flair and a cutting edge and we believe this backline provides that," Ryan added. "We are heading for a confrontational environment, an environment in which Bourgoin have a good record and we must be ready to handle that.
"The pool is very much still alive which is why these two back-to-back games are so important. Preparation has been good, we have learnt a great deal over the last year or so in this competition about how to win games like this and we must put that into practice tomorrow."
Ryan's forward pack is also experienced. Nick Wood, who signed a new two-year contract extension last week, starts at loose-head, Olivier Azam at hooker and Carlos Nieto at tight-head.
Peter Buxton will skipper the side from the second row alongside Alex Brown. That allows the tough tackling Alasdair Strokosch to wear number six, Akapusi Qera comes in for Hazell and Gareth Delve, outstanding against the Dragons, wears eight.
"Everyone appreciates the intensity levels of this game and central to that will be the performance of our forwards," Ryan said. "We have stacked up well in this competition and we must maintain that.
"This is a game we are thoroughly looking forward to as a group because of its significance."
Ryan has split his bench four-three in favour of his forwards. Andy Titterrell and Christian Califano will be the front row replacements Will James will cover lock and Luke Narraway the back row.
Scrum-half Gareth Cooper, stand-off Chris Paterson and utility back Leon Lloyd are the three-quarter replacements.
GLOUCESTER (v Bourgoin, tomorrow): Olly Morgan; James Simpson-Daniel, Mike Tindall, Anthony Allen, Iain Balshaw; Ryan Lamb, Rory Lawson; Nick Wood, Olivier Azam, Carlos Nieto, Peter Buxton (capt), Alex Brown, Alasdair Strokosch, Akapusi Qera, Gareth Delve. Reps: Andy Titterrell, Christian Califano, Will James, Luke Narraway, Gareth Cooper, Chris Paterson, Leon Lloyd.
Speaking after the 15-3 Aviva Premiership defeat at Northampton, Director of Rugby David Humphreys couldn't criticise his team's effort in difficult conditions, but pinpointed the errors and indiscipline that allowed Stephen Myler to kick the home team to victory.
A handful of the Gloucester Rugby Mo-Bros visited Pride Hair Salon in Gloucester on Wednesday afternoon to have the final touches applied to their Movember efforts, and the team captain Jacob Rowan spoke to GRTV ahead of the final few days of the month.
Northampton away was the first Gloucester game under David Humphreys last season, but the Director of Rugby told the local media that the Cherry and Whites are a different proposition compared to 12 months ago and are looking forward to the challenge.
Having skippered Gloucester against the Barbarians last week, Nick Wood once again wore the captain's armband on Monday evening as Gloucester United kicked off their Aviva Premiership A League campaign with a bonus point win at Leicester.
Gloucester recorded a 32-20 win over La Rochelle on Thursday evening, and second row Jeremy Thrush was thrilled to pick up the victory on his first taste of a trip to France and the hostile atmosphere.
Gloucester were forced to battle for their 33-20 victory in La Rochelle on Thursday evening, something that centre Bill Meakes said that he and the squad were well prepared for as well as thanking the travelling support for the part they played.
After missing out on Gloucester's two recent European fixtures, Jonny May is back on the left wing for Friday evening's Aviva Premiership fixture at Northampton, while Mariano Galarza is named in the matchday squad for the first time this season.