GLOUCESTER'S head coach Dean Ryan has named a side containing 12 full internationals for the visit of Newcastle Falcons in the EDF Energy Cup tomorrow (3pm).
Australian international hooker Jeremy Paul will make his debut in Gloucester's front row alongside loose-head prop Alasdair Dickinson, who also starts for the first time this season and Christian Califano completes the front three.
While Alex Brown takes a break in the second row, Marco Bortolami gets the opportunity to forge a partnership with Will James at lock and will also skipper the side for the first time this season.
In the back row, Peter Buxton, who has featured in every match so far this season, is not included which means Alasdair Strokosch will wear number six. Akapusi Qera will start his second game in succession on the openside and Adam Balding wears number eight for his first start this season.
"We see this as a great opportunity to assess our options, continue the integration of a number of players who have not had a great deal of rugby with us this season and show some sort of kick-back from our defeat last weekend," said head coach Dean Ryan.
"I think you only have to look at this side to see how important this game is for us and our squad strength reflects that. We were disappointed with a number of the processes against London Irish last week and we want to put that right.
"It is important we see the likes of Jeremy Paul involved with us - he has been fantastic since his arrival - and we also want to see other combinations in action as soon as possible."
There will also be a new half-back pairing where Rory Lawson partners Chris Paterson and James Simpson-Daniel returns from a three-week hamstring injury to partner Anthony Allen in centre.
The back three is also shifted around - Mark Foster comes in for his first start of the season in place of James Bailey, Iain Balshaw retains his place at full-back and Karl Pryce comes in on the wing for his first start.
"We have a lot of talent and a lot of options available to us and we want a platform to move into for forthcoming games," Ryan added.
"There is an opportunity for us to move into a more stable environment going forward but we want guys to put their hands up and show us what they can do and for that reason we view it as a great opportunity."
The only players not to be capped at senior level in the starting XV are Balding, Foster and Pryce.
On the bench, Andy Titterrell and Jack Forster are the front row options, Jonathan Pendlebury returns to the matchday squad and Luke Narraway completes the forward options.
Gareth Cooper, who has been out of action for a fortnight with a hamstring strain, returns alongside Willie Walker and Karl Pryce.
"Gareth Delve was close to inclusion but this game is a week too early - he is doing everything the squad is now and is making progress," Ryan added.
GLOUCESTER (v Newcastle, tomorrow, 3pm): Iain Balshaw; Karl Pryce, James Simpson-Daniel, Anthony Allen, Mark Foster; Chris Paterson, Rory Lawson; Alasdair Dickinson, Jeremy Paul, Christian Califano, Marco Bortolami (capt), Will James, Alasdair Strokosch, Akapusi Qera, Adam Balding. Reps: Andy Titterrell, Jack Forster, Jonathan Pendlebury, Luke Narraway, Gareth Cooper, Willie Walker, James Bailey.
The West Country Challenge Cup fixture against the Exeter Chiefs at the Memorial Stadium in Bristol on Saturday (kick off 3pm) will be Gloucester's last chance to work on things like new combinations says Director of Rugby, David Humphreys.
Speaking after the 30-21 West Country Challenge Cup defeat at Bath, Director of Rugby David Humphreys spoke of the improvements his team are making as preseason progresses but acknowledges that there is still work to do ahead of the start of the Aviva Premiership.
Speaking to the local media ahead of Saturday's trip to Bath Rugby in the West Country Challenge Cup, front rower Nick Wood spoke of the hard work put in across the extended preseason and highlighted the competition for front row spots in the squad.
Gloucester have named a 30 man squad for the latest round of West Country Challenge Cup action against Bath on Saturday, with Director of Rugby David Humphreys stressing the need to keep an eye on player workload ahead of what will be a long, tough season.
Describing the 50-7 West Country Challenge Cup win over Bath on Sunday as a '...good hit out...', wing Charlie Sharples admitted that it had been a good opportunity to put into practice things that the squad have been trying out in training in recent weeks.
Speaking to the local media after the 50-7 victory over Bath Rugby on Sunday, David Humphreys was happy with his squad's effort, with the most important aspect being the game time earned by his players.
Gloucester make wholesale changes to the side that started at Exeter last Saturday as they prepare to take on Bath at the Memorial Stadium, Bristol on Sunday in the West Country Challenge Cup (kick off 3pm). The Director of Rugby told GRTV that the players are raring to go and that he's looking forward to seeing different combinations in action.
Speaking ahead of the West Country Challenge Cup meeting with Bath Rugby this Sunday, front rower Paddy McAllister explained how he was looking forward to running out in Cherry and White after a preseason packed full of hard work.
A late penalty from Exeter fly-half Will Hooley gave the Chiefs a narrow 33-31 West Country Challenge Cup win over a heroic Gloucester outfit in a bruising encounter at the Memorial Stadium on Saturday.
Gloucester Rugby will play their fourth and final West Country Challenge Cup fixture this weekend (Memorial Stadium, Bristol, 3pm) against the Exeter Chiefs, and have named a side featuring a host of first regulars.
On Wednesday evening, Gloucester Rugby duo Mark Atkinson and Tom Savage visited local rugby club Hardwicke and Quedgeley Harlequins RFC for the first session as part of the Gloucester Rugby in Local Clubs coaching initiative.