Meanwhile, Jim Hamilton retains his place in the second row at the expense of Kellock, with Nathan Hines dropping to the bench and Alasdair Strokosch starts again at blindside flanker.
England are in action on Saturday against Romania and have recalled Mike Tindall in the centre.
Mark Cueto makes his first appearance of the tournament on the wing following a back injury, while Jonny Wilkinson takes over from Toby Flood at fly-half.
Steve Thompson, Alex Corbisiero, Louis Deacon and Tom Croft also return.
Scotland:
C Paterson; M Evans, N De Luca, G Morrison, S Lamont; R Jackson, R Lawson (capt); A Jacobsen, R Ford, G Cross, R Gray, J Hamilton, A Strokosch, J Barclay, K Brown.
Replacements:
D Hall, A Dickinson, N Hines, R Vernon, M Blair, D Parks, S Danielli.
England:
Ben Foden (Northampton Saints); Chris Ashton (Northampton Saints), Manu Tuilagi (Leicester Tigers), Mike Tindall (Gloucester Rugby), Mark Cueto (Sale Sharks); Jonny Wilkinson (Toulon), Ben Youngs (Leicester Tigers); Alex Corbisiero (London Irish), Steve Thompson (London Wasps), Dan Cole (Leicester Tigers), Louis Deacon (Leicester Tigers), Tom Palmer (Stade Francais), Tom Croft (Leicester Tigers), Lewis Moody (Bath Rugby, capt), James Haskell (Ricoh Black Rams).
Replacements:
Lee Mears (Bath Rugby), David Wilson (Bath Rugby), Simon Shaw (Unattached), Tom Wood (Northampton Saints), Richard Wigglesworth (Saracens), Toby Flood (Leicester Tigers), Delon Armitage (London Irish).
