He only moved to Kingsholm from London Welsh in the summer and made his first Gloucester appearance as a replacement against Northampton Saints in the Guinness Premiership.
He has gone on to make five starts and four replacement appearances and impressed with his work around the park and ability to play both sides of the scrum.
James Haskell comes in at number eight after Jordan Crane - who started in the 18-9 defeat by Australia - was among 10 players released to their clubs.
Veteran prop Duncan Bell, 35, will make his first Test start since 2005 after an injury to David Wilson.
Hooker Dylan Hartley replaces Steve Thompson while Paul Hodgson is preferred to Danny Care at scrum-half.
Monye; Cueto, Hipkiss Geraghty, Banahan; Wilkinson, Hodgson; Payne, Hartley, Bell, Deacon, Borthwick (capt), Croft, Moody, Haskell.
Thompson, Doran-Jones, Lawes, Worsley, Care, Goode, Erinle.