Uncapped Gloucester prop Nick Wood has been named amongst the replacements for England for Saturday's clash with the Barbarians.
Wood's selection means that he could potentially be lining up against Gloucester team mate Greg Somerville who starts at tight head for the Barbarians.
Lewis Moody is back in the England side after a 15 month absence and six players will make their first starts.
World Cup winner Moody, a Guinness Premiership winner and Heineken Cup finalist with Leicester Tigers this season, hasn't featured for England since the opening game of the 2008 RBS 6 Nations against Wales.
The 30-year-old lines up in the back-row with Nick Easter and uncapped Harlequins flanker Chris Robshaw, the Guinness Premiership's Player of the Season.
The five other players making their first start are Dylan Hartley and Ben Foden, who were European Challenge Cup winners with Northampton Saints last week, and Harlequins centre Jordan Turner-Hall, Bath Rugby wing Matt Banahan and Newcastle Falcons prop David Wilson.
England team manager Martin Johnson also calls on captain Steve Borthwick (Saracens) and Delon Armitage (London Irish), who played throughout the 2009 RBS 6 Nations campaign, while hooker Steve Thompson and flanker James Haskell are among the replacements.
The game will be England's final appearance of the 2008/09 season at Twickenham before they prepare for their two Test series against Argentina at Old Trafford on June 6 and Salta, Argentina, on June 13.
Delon Armitage (London Irish); Ben Foden (Northampton Saints), Jamie Noon (Newcastle Falcons), Jordan Turner-Hall (Harlequins)*, Matt Banahan (Bath Rugby)*; Andy Goode (CA Brive), Danny Care (Harlequins); Tim Payne (London Wasps), Dylan Hartley (Northampton Saints), David Wilson (Newcastle Falcons)*; Steve Borthwick (Saracens, captain), Louis Deacon (Leicester Tigers); Chris Robshaw (Harlequins)*, Lewis Moody (Leicester Tigers)
8 Nick Easter (Harlequins)
Steve Thompson (CA Brive), Nick Wood (Gloucester Rugby)*, Chris Jones (Sale Sharks), Steffon Armitage (London Irish), James Haskell (London Wasps), Paul Hodgson (London Irish), Tom May (Newcastle Falcons)*
* Uncapped players (note that this is not a Test match and caps are not awarded for this game).
Billy Twelvetrees spoke to Gloucester Rugby TV after contributing fifteen points for the team at Twickenham. Despite the defeat, Twelvetrees praised the effort shown by his team, but rued silly errors that gifted London Wasps easy points.
Director of Rugby Nigel Davies was quickly able to identify a couple of key areas where Gloucester weren't quite good enough on the day, when he spoke to the media following defeat in The Stinger at Twickenham.
Huia Edmonds spoke to Gloucester Rugby TV this week ahead of Gloucester's clash with London Wasps in #TheStinger. The Australian hooker is yet to play at Twickenham and is excited at the prospect and putting things right on the pitch.
The bitter disappointment of losing against London Wasps in the Amlin Challenge Cup less than a fortnight ago, will give Gloucester ample motivation against the same opponent at Twickenham on Saturday says Director of Rugby Nigel Davies.
Billy Twelvetrees spoke to Gloucester Rugby TV following the 17-18 loss to Bath Rugby in Round Nineteen of Aviva Premiership Rugby. The Gloucester skipper said he was proud of the desire shown by his team at the end of a tough afternoon.
Nigel Davies spoke to Gloucester Rugby TV following the gutting 17-18 reverse to Bath on Saturday afternoon. The Director of Rugby expressed his pride at the efforts from his players and thanked the supporters for their incredible backing.
Nick Wood spoke to Gloucester Rugby TV this week ahead of Saturday's West Country derby clash with Bath Rugby. The front rower called on the squad to make a strong start and get the Kingsholm crowd behind them
Director of Rugby Nigel Davies admits that it's been a tough week at Gloucester Rugby following defeat at London Wasps last weekend, but that he's looking for his team to rise to the occasion for the huge game at home to Bath Rugby on Saturday.
Gloucester Rugby's trip to Twickenham ended in a 38-30 defeat to London Wasps in the sunshine. The hosts ran in 5 tries to Gloucester's three on a tough afternoon that despite plenty of promise saw Gloucester let down by errors.