The Cherry and Whites kick off the Premiership season at home to Sale Sharks before travelling to Saracens the following week.
Northampton Saints are the next visitors to Kingsholm, before Gloucester travel to Newcastle and round off the opening block of five games at home to Exeter Chiefs.
The Premiership then takes a back seat for a couple of weeks as the first batch of European fixtures take place, and Director of Rugby Nigel Davies admitted that getting off to a good start is crucial to Gloucester's ambitions.
"Last year maybe by saying top four we aimed a little too low. Like every other team we want to win the Premiership.
"We know what that will take in the league, to give us the best chance to do that in the knockout stages. There's only one team that's finished outside the top two in the league that's won the knockout stages.
"So we know what we've got to do, it's quite clear now we've seen the fixtures where we need to pick up the points. And there's no doubt there will be ups and downs along the way.
"But to stay focused on the task in hand we have to realise in any one time in the season exactly where we are, by breaking down each game into how many points we want to gain from it.
"That will give us a firm grip on where we need to be. So that block of five games at the start of the season is going to be hugely significant as to how the rest of the season pans out.
"We're not looking much further ahead than that block of games right now. You've got to go one bite at a time, at the same time as realising the bigger picture.
"We've already planned how many points we want from the season, and where we aim to pick those up, and we'll be reassessing those targets constantly.
"We'll take it one step at a time, and if we were to find ourselves looking at February right now, then we would not be completely focused on the absolute main challenge.
"That block of five is vital, and when we come off the back of that we can reassess."