The challenge of playing two fixtures means that Ryan has to rely upon the depth of his squad particularly with Gloucester's final regular season of the Guinness Premiership season taking place at Wasps on Saturday afternoon.

There is a new half back pairing as Carlos Spencer, cup tied on Saturday, returns to the starting line up and partners Gareth Cooper.

Mike Tindall and Iain Balshaw are both still unavailable for selection but Olly Barkley starts at inside centre and Charlie Sharples comes in for Olly Morgan at full back.

Up front, there is a new look front row in Alasdair Dickinson, Scott Lawson and Carlos Nieto and Adam Eustace comes into the second row but Greg Somerville, Alex Brown, Luke Narraway, Akapusi Qera and Gareth Delve remain.

Results over the weekend leave Gloucester currently in sixth place in the Guinness Premiership table but a bonus point win would lift the Cherry and Whites to third place based on games won.

Tickets are still available for the game all areas of the ground.

Gloucester Rugby:

Charlie Sharples; Matthew Watkins, James Simpson-Daniel, Olly Barkley, Mark Foster; Carlos Spencer, Gareth Cooper; Alasdair Dickinson, Scott Lawson, Carlos Nieto; Adam Eustace, Alex Brown; Luke Narraway, Akapusi Qera, Gareth Delve (capt)

Replacements:

Olivier Azam, Greg Somerville, Marco Bortolami, Apo Satala, Rory Lawson, Ryan Lamb, Olly Morgan