The only other change to the back line that started against Sale Sharks last weekend sees Martyn Thomas replace Shane Monahan on the left wing.
Nigel Davies also keeps faith with the majority of the pack that was on duty against the Sharks, although Darren Dawidiuk is back at hooker for his first appearance since September 22nd.
It's second versus third in the Aviva Premiership, with the teams both on 28 points, and both fixtures last season were incredibly tight.
Saracens have slipped to back to back defeats in all competitions but have only lost once in their last 17 Premiership fixtures at Vicarage Road.
Accordingly, Director of Rugby Nigel Davies knows that Sunday's game will present a stern test.
"I'm sure Saracens won't have been impressed with their performance, or their result, against Worcester last Friday and will pick it up against us this weekend.
"It's a difficult place to go and play, it's one of the smallest pitches in the league, and they know how to play that field.
"You have to be smart. You have to play a similar game to them in some ways. But you also have to be prepared to step up and take your game to them.
"They play good territory, they have a big chase and put a lot of pressure on to you. If you're not ready for it, then you'll get caught out."
Gloucester Rugby:
Rob Cook; Charlie Sharples, Tim Molenaar, Mike Tindall, Martyn Thomas; Billy Twelvetrees, Jimmy Cowan; Dan Murphy, Darren Dawidiuk, Rupert Harden; Will James, Jim Hamilton (capt); Tom Savage, Akapusi Qera, Sione Kalamafoni
Replacements:
Koree Britton, Nick Wood, Shaun Knight, Peter Buxton, Matt Cox, Dan Robson, Tim Taylor, Shane Monahan
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