Each of the colleges is linked one of the 14 England Rugby Academies - Hartpury with Gloucester Rugby and Ivybridge with Exeter Chiefs.
Hartpury included current England Under 18 internationals Ryan Mills and Dan Robson in their side as they powered past Twyford 46-8. Wing Ian Clark and lock Rob Langley shared four tries with Mills supplying five conversions and two penalties.
Ivybridge had a tighter semi-final, beating Northampton's Moulton College 19-8, but the two finalists were separated by only a single point when they met earlier this year.
"We played them in January in a very tight game and did well to snatch the win," said Hartpury's Junior Rugby Academy Director Alan Martinovic. "They're a strong side, we know that. There's more at stake now and we'll have to be at our best."
Martinovic, who coached Colston's to seven Daily Mail RBS Schools Cup finals, is enthusiastic about the AASE scheme - now in its third year - and the new competition.
"The AASE League will develop into a very strong competition, it's made an excellent start and everyone's done a good job putting it in place," he said.
"There are now AASE sides as strong as any traditional schools sides in the country and there's now a much wider range of opportunities for young players. As far as rugby's concerned, having more choice has got to be a good thing."
Ivybridge's AASE scheme is run by former Saracens flanker and England Sevens star Tony Roques and his former Exeter Chiefs teammate Danny Porte.
Their side needed all their resolve to get past Moulton according to Exeter's Assistant Academy Manager Rob Gibson.
Scrum half Ben Spencer scored two tries, Sam Hill got the other and Dan Mugford added two conversions for a team that included highly-rated England U18 hooker Koree Britton and second row Addison Lockley.
"It was a cracking game, they threw everything at us and for 15 minutes in the first half they were camped on our line," said Gibson.
"We changed a couple of things at half time, were able to generate quicker ball and two tries early in the second half took the wind out of their sails."
Gibson added: "We've always tried to find the toughest fixtures we can and this has provided us with something to focus on. The only way the players will learn is to play in tough games.
"Overall it's a fantastic programme and we've got guys like Tony [Roques] and Dan [Porte] who can help the players look after themselves on and off the field. It'll be a huge bonus for England rugby in the future."
AASE League finals, Wednesday 28th April, Henley
Bowl: Oaklands or Exeter v Truro College (11.30am)
Plate: Prince Henrys or Filton v St Paul's (1.30pm)
Championship: Ivybridge v Hartpury (3.00pm)
Semi final results
Bowl semi finals: Oaklands 52 Exeter 16, Truro bt Worcester w/o
Plate semi finals: Prince Henry's 22 Filton 37, St Paul's 20 Myerscough 3
Championship semi finals: Moulton 8 Ivybridge 19, Twyford 8 Hartpury 46