Five players will win their first caps for England in the opening game of the RBS U20 Six Nations against Wales at Gloucester on Friday night (7.45pm). Gloucester's Freddie Burns and Shaun Knight will both start with Jonny May named amongst the replacements.
Full back Tom Catterick (Newcastle Falcons), wing Sam Smith (Harlequins), lock Calum Green (Leicester Tigers), flanker Will Welch and No.8 Alex Gray (both Newcastle Falcons) are all in the starting line-up
They slot into an experienced side that contains seven survivors from last year's IRB Junior World Championship in Tokyo, where England were beaten finalists for the second year in succession.
Back in action after missing last month's 61-7 warm-up win against Cambridge University are established Guinness Premiership performers James Gaskell (Sale Sharks), Tom Homer (London Irish) and Rory Clegg (Harlequins).
Gloucester's Freddie Burns will be at fly half on his home ground with Clegg and Homer making up an exciting midfield trio.
"We're excited about the potential of this group and we've got a nice blend of young players coming into the side together with those who were involved with us last year," said head coach Mark Mapletoft.
"We want to play an exciting brand of rugby at a high tempo and they've all bought into that.
"We're under no illusions that Wales will be a really difficult test for us, though, and they continue to produce lots of talented young players. Both sides will want to play and move the ball, so it should make for a great contest at Kingsholm."
15 Tom Catterick (Newcastle Falcons)
14 Will Hurrell (Leicester Tigers)
13 Tom Homer (London Irish)
12 Rory Clegg (Harlequins)
11 Sam Smith (Harlequins)
10 Freddie Burns (Gloucester Rugby)
9 Sam Harrison (Leicester Tigers)
1 Joe Marler (Harlequins)
2 Jamie George (Saracens)
3 Shaun Knight (Gloucester Rugby)
4 Calum Green (Leicester Tigers)
5 James Gaskell (Sale Sharks)
6 Will Welch (Newcastle Falcons)
7 Jacob Rowan (Leeds Carnegie, captain)
8 Alex Gray (Newcastle Falcons)
16 Arthur Ellis (London Wasps)
17 Lee Imiolek (Sale Sharks)
18 Charlie Matthews (Harlequins)
19 Jackson Wray (Saracens)
20 Sam Stuart (Harlequins)
21 Jonathan Joseph (London Irish)
22 Jonny May (Gloucester Rugby)
Speaking straight after the game, skipper Billy Twelvetrees told GRTV that losing at home to Bath, in front of a tremendous home support, was desperately disappointing and that the whole team were hurting in the dressing room.
Speaking to the local media this week, Richard Hibbard expressed his excitement ahead of the West Country derby and that there is an extra spring in the step of the Cherry and Whites ahead of the tough challenge.
With such a short turnaround between the two games, and Gloucester looking to reintegrate several players into the line-up after the Autumn international series, Tom Savage told GRTV that the Cherry and Whites will keep changes to a minimum for the European Rugby Challenge Cup game in Zebre on Saturday.
On a tough evening at Kingsholm, Gloucester could escape neither a suffocating Bath defence, nor the whistle of referee Greg Garner as six penalties and a penalty try paved the way to a 39-16 win for the visitors.