However, as per the format last season, Gloucester will play the teams in pool of the competition which means fixtures against the Dragons, Leeds Carnegie, London Irish and Saracens.
Terry Burwell, LV= Cup Director, said:
"Last season's tournament produced some great rugby and in the final, one of the stand out games of the season."
"We are very much looking forward to the second year of a competition structure that not only helps players, coaches and officials develop but also provides more revenue potential for the English Premiership clubs and the Welsh regions."
"We have a committed broadcaster in Sky Sports for the next five years, plus coverage in Wales from S4C, and we would like to thank LV= for supporting the Rugby Football Union, Premiership Rugby, the Welsh Rugby Union and the teams themselves in the delivery of elite knockout rugby."
David Radford, LV= Group Marketing Director, said:
"LV= is strongly committed to rugby and our sponsorship of the Anglo-Welsh tournament. We are looking forward to another year of high quality, competitive rugby."
2010-11 LV= Cup structure
Round 1 (weekend of November 6, 2010)
Bath Rugby v Cardiff Blues
Exeter Chiefs v London Wasps
Newcastle Falcons v Ospreys
Leicester Tigers v Harlequins
Sale Sharks v London Irish
Saracens v Northampton Saints
Dragons v Gloucester Rugby
Scarlets v Leeds Carnegie
Round 2 (weekend of November 13, 2010)
Harlequins v Newcastle Falcons
London Wasps v Bath Rugby
Cardiff Blues v Exeter Chiefs
Ospreys v Leicester Tigers
Gloucester Rugby v Saracens
Leeds Carnegie v Sale Sharks
Northampton Saints v Dragons
London Irish v Scarlets
Round 3 (weekend of January 29, 2011)
Exeter Chiefs v Leicester Tigers
London Wasps v Harlequins
Bath Rugby v Newcastle Falcons
Cardiff Blues v Ospreys
Leeds Carnegie v Gloucester Rugby
Sale Sharks v Dragons
London Irish v Northampton Saints
Scarlets v Saracens
Round 4 (weekend of February 5, 2011)
Leicester Tigers v Bath Rugby
Newcastle Falcons v Exeter Chiefs
Ospreys v London Wasps
Harlequins v Cardiff Blues
Gloucester Rugby v London Irish
Saracens v Sale Sharks
Northampton Saints v Leeds Carnegie
Dragons v Scarlets
Semi finals (weekend of March 12, 2011, venue TBC)
Final (weekend of March 19, 2011, venue TBC)
• If the winner of the competition is an English club, they will qualify for the following season's Heineken Cup
• The LV= Cup is a separate tournament to the British & Irish Cup which involves the 12 teams from the RFU Championship (the level below Aviva Premiership Rugby), six club sides from the Welsh Principality Premiership, Irish provinces Munster, Leinster and Ulster and three Scottish sides.
• The LV= Cup is a 16-team competition involving the 12 Aviva Premiership Rugby clubs and 4 Welsh regions
• Played in four pools of four with three English clubs and one Welsh region in each pool
• English clubs have been allocated to the pools depending on their finish in last season's Premiership
• Welsh regions have been allocated to the pools to avoid repeating fixtures from the Heineken and Amlin Challenge cups where possible
• Teams in Pool 1 play teams in Pool 4 and teams in Pool 2 play teams in Pool 3
• Each team plays four pool matches - two home and two away - with the top team from each pool qualifying for the semi finals.