French hooker Olivier Azam returns to the Gloucester starting line-up for Saturday's Zurich Premiership encounter away at London Irish (Sat 26 Mar, kick off 5pm).
30 year-old Azam, who has been a replacement in the last few games, makes his first start since late October after a shoulder injury.
The French front row man starts ahead of Mefin Davies, who was ruled out late in the week with a dead leg after taking a knock to it during last weekend's Wales game. Azam's fellow hooker and countryman Noel Curnier backs-up from the bench.
Brad Davies and Alex Page form the half-back partnership for the Irish clash, with Andy Gomarsall missing out on the matchday 22. England Sevens captain Simon Amor provides cover from the bench.
James Simpson-Daniel moves back to the wing, and Kiwi centre Nathan Mauger starts in midfield alongside Terry Fanolua.
England open-side Andy Hazell returns to the starting line-up after international duties, and partners captain Adam Balding and Peter Buxton in the back-row.
The Kingsholm Supporters Mutual-organised coaches for supporters leave Kingsholm at 1pm for the match that kicks off at 5pm.
The Clubhouse bar at Kingsholm will open at 1pm on Saturday for the England football match and for the Gloucester game at 5pm.
15. Jon Goodridge
14. Marcel Garvey
13. Nathan Mauger
12. Terry Fanolua
11. James Simpson-Daniel
10. Brad Davies
9. Alex Page
1. Nick Wood
2. Olivier Azam
3. Gary Powell
4. Adam Eustace
5. Alex Brown
6. Peter Buxton
7. Andy Hazell
8. Adam Balding (c)
16. Noel Curnier
17. Terry Sigley
18. James Forrester
19. Jake Boer
20. Simon Amor
21. Seti Kiole
22. Olly Morgan
Speaking with the local media before the Gloucester team set off on the long trip north to Newcastle, Director of Rugby David Humphreys discussed his team selection and stated that Friday night's meeting will be a challenging one.
Speaking to the local media on Thursday, Matt Kvesic was looking forward to the trip to Newcastle Falcons, and the captain is looking to lead from the front with plenty for the Cherry and Whites to work on.
Gloucester saw a 12-0 lead overturned by Harlequins on Friday night as the visitors ran out 22-15 winners. After the game, Director of Rugby David Humphreys spoke about missed opportunities on the night.
Speaking to the local media on Thursday, James Hudson explained his excitement for tonight's game with Harlequins and that he is backing the Cherry and White squad to impress during the next set of Aviva Premiership games.
Gloucester Rugby welcomed back a set of returning internationals at the start of this week, and one of them, James Hook is pleased to be back, and ready to get back to business in a Cherry and White shirt.
After the huge success of the Darts evening in March, Gloucester Rugby and events sponsors Worthington's are pleased to present an evening with Darts Legends Eric Bristow, Keith Deller, Bobby George and Wayne Mardle hosted by Russ Bray on Tuesday 9 December.