Gloucester make a number of changes to the team that travels to NEC Harlequins for Saturday's Zurich Premiership game (Sat 5 Feb, Stoop, kick off 2pm).
Four Kingsholm forwards are involved in the England Vs Wales game in Cardiff on the same day, with Andy Hazell starting for England, James Forrester and Phil Vickery on the bench, and Mefin Davies lining up for Wales.
South African prop Christo Bezuidenhout comes in at loose-head for Gloucester, with Terry Sigley moving to the number three shirt. James Parkes replaces Mefin Davies at hooker, and Frenchman Noel Curnier is named on the bench.
Mark Cornwell starts in the second row alongside Alex Brown, and Peter Buxton starts at blind-side flanker, with captain Jake Boer moving to open-side in place of Hazell.
James Simpson-Daniel makes his return from injury and partners Seti Kiole on the wings. Marcel Garvey misses out due to mumps.
Andy Gomarsall and Henry Paul both returned from England training in the middle of the week and line-up in the Gloucester back line.
Quins have advised supporters without tickets not to travel, as they are not expecting tickets to be available on the day.
15. Jon Goodridge
14. Seti Kiole
13. Terry Fanolua
12. Henry Paul
11. James Simpson-Daniel
10. Duncan McRae
9. Andy Gomarsall
1. Christo Bezuidenhout
2. James Parkes
3. Terry Sigley
4. Mark Cornwell
5. Alex Brown
6. Peter Buxton
7. Jake Boer (c)
8. Adam Balding
Replacements: 16. Noel Curnier
17. Nick Wood
18. Adam Eustace
19. Luke Narraway
20. Alex Page
21. Nathan Mauger
22. Mark Foster
Speaking after the 55-0 win over CA Brive, Jonny May told GRTV that he's delighted that the team's hard work is starting to pay dividends but was equally happy for his friend and team mate, Charlie Sharples, on what was a big night for his fellow winger.
Speaking to the local media this week, David Humphreys insisted that Gloucester are looking forward to kicking off the new European Rugby Challenge Cup against Brive on Thursday evening, although an unfamiliar opponent and a five day turnaround will pose a challenge.
Director of Rugby David Humphreys felt that his Gloucester side put themselves in a position to put Saracens under real pressure at Allianz Park on Saturday, praising his team's commitment and defence, while admitting that a lack of accuracy hit their chances in the second half.
Speaking to the local media at Allianz Park, Tom Savage was disappointed after the defeat at Saracens, but claimed Gloucester did plenty of good things and could've taken more than a losing bonus point.