Gloucester make a number of changes to the team that travels to NEC Harlequins for Saturday's Zurich Premiership game (Sat 5 Feb, Stoop, kick off 2pm).
Four Kingsholm forwards are involved in the England Vs Wales game in Cardiff on the same day, with Andy Hazell starting for England, James Forrester and Phil Vickery on the bench, and Mefin Davies lining up for Wales.
South African prop Christo Bezuidenhout comes in at loose-head for Gloucester, with Terry Sigley moving to the number three shirt. James Parkes replaces Mefin Davies at hooker, and Frenchman Noel Curnier is named on the bench.
Mark Cornwell starts in the second row alongside Alex Brown, and Peter Buxton starts at blind-side flanker, with captain Jake Boer moving to open-side in place of Hazell.
James Simpson-Daniel makes his return from injury and partners Seti Kiole on the wings. Marcel Garvey misses out due to mumps.
Andy Gomarsall and Henry Paul both returned from England training in the middle of the week and line-up in the Gloucester back line.
Quins have advised supporters without tickets not to travel, as they are not expecting tickets to be available on the day.
15. Jon Goodridge
14. Seti Kiole
13. Terry Fanolua
12. Henry Paul
11. James Simpson-Daniel
10. Duncan McRae
9. Andy Gomarsall
1. Christo Bezuidenhout
2. James Parkes
3. Terry Sigley
4. Mark Cornwell
5. Alex Brown
6. Peter Buxton
7. Jake Boer (c)
8. Adam Balding
Replacements: 16. Noel Curnier
17. Nick Wood
18. Adam Eustace
19. Luke Narraway
20. Alex Page
21. Nathan Mauger
22. Mark Foster
With such a short turnaround between the two games, and Gloucester looking to reintegrate several players into the line-up after the Autumn international series, Tom Savage told GRTV that the Cherry and Whites will keep changes to a minimum for the European Rugby Challenge Cup game in Zebre on Saturday.
Gloucester travel to Italy this weekend to take on Zebre in Round Four of the European Rugby Challenge Cup. The Cherry and Whites defeated the Italian side 35-10 last Sunday, but Director of Rugby David Humphreys is looking for an improved performance in the return fixture.
Skipper Billy Twelvetrees, speaking to GRTV after the 35-10 over Zebre, was happy with the bonus point win over the Italian side but admitted Gloucester will need to tighten up for the return fixture in Parma.
Matt Kvesic was a try scorer and recipient of the Man of the Match award in Sunday's 35-10 European Rugby Challenge Cup win over Zebre. He praised the Italian side for their spirited opposition and admitted that next week's return game will be a tough one.
After a tense opening half hour in Parma, the game turned just before half time as the home team had David Odiete red carded and Gloucester took full advantage, running in three second half tries to secure the bonus point and the victory over Zebre by 32 points to 16.