Gloucester make a number of changes to the team that travels to NEC Harlequins for Saturday's Zurich Premiership game (Sat 5 Feb, Stoop, kick off 2pm).
Four Kingsholm forwards are involved in the England Vs Wales game in Cardiff on the same day, with Andy Hazell starting for England, James Forrester and Phil Vickery on the bench, and Mefin Davies lining up for Wales.
South African prop Christo Bezuidenhout comes in at loose-head for Gloucester, with Terry Sigley moving to the number three shirt. James Parkes replaces Mefin Davies at hooker, and Frenchman Noel Curnier is named on the bench.
Mark Cornwell starts in the second row alongside Alex Brown, and Peter Buxton starts at blind-side flanker, with captain Jake Boer moving to open-side in place of Hazell.
James Simpson-Daniel makes his return from injury and partners Seti Kiole on the wings. Marcel Garvey misses out due to mumps.
Andy Gomarsall and Henry Paul both returned from England training in the middle of the week and line-up in the Gloucester back line.
Quins have advised supporters without tickets not to travel, as they are not expecting tickets to be available on the day.
15. Jon Goodridge
14. Seti Kiole
13. Terry Fanolua
12. Henry Paul
11. James Simpson-Daniel
10. Duncan McRae
9. Andy Gomarsall
1. Christo Bezuidenhout
2. James Parkes
3. Terry Sigley
4. Mark Cornwell
5. Alex Brown
6. Peter Buxton
7. Jake Boer (c)
8. Adam Balding
Replacements: 16. Noel Curnier
17. Nick Wood
18. Adam Eustace
19. Luke Narraway
20. Alex Page
21. Nathan Mauger
22. Mark Foster
Speaking with the local media before the Gloucester team set off on the long trip north to Newcastle, Director of Rugby David Humphreys discussed his team selection and stated that Friday night's meeting will be a challenging one.
Speaking to the local media on Thursday, Matt Kvesic was looking forward to the trip to Newcastle Falcons, and the captain is looking to lead from the front with plenty for the Cherry and Whites to work on.
Gloucester saw a 12-0 lead overturned by Harlequins on Friday night as the visitors ran out 22-15 winners. After the game, Director of Rugby David Humphreys spoke about missed opportunities on the night.
Speaking to the local media on Thursday, James Hudson explained his excitement for tonight's game with Harlequins and that he is backing the Cherry and White squad to impress during the next set of Aviva Premiership games.
Gloucester Rugby welcomed back a set of returning internationals at the start of this week, and one of them, James Hook is pleased to be back, and ready to get back to business in a Cherry and White shirt.
After the huge success of the Darts evening in March, Gloucester Rugby and events sponsors Worthington's are pleased to present an evening with Darts Legends Eric Bristow, Keith Deller, Bobby George and Wayne Mardle hosted by Russ Bray on Tuesday 9 December.
In a unique collaboration, the West's big three rugby rivals -Bristol Rugby, Bath Rugby and Gloucester Rugby - have joined forces to launch 'Break The Cycle' for 2015, and it's bigger and better than ever before.