Gloucester make a number of changes to the team that travels to NEC Harlequins for Saturday's Zurich Premiership game (Sat 5 Feb, Stoop, kick off 2pm).
Four Kingsholm forwards are involved in the England Vs Wales game in Cardiff on the same day, with Andy Hazell starting for England, James Forrester and Phil Vickery on the bench, and Mefin Davies lining up for Wales.
South African prop Christo Bezuidenhout comes in at loose-head for Gloucester, with Terry Sigley moving to the number three shirt. James Parkes replaces Mefin Davies at hooker, and Frenchman Noel Curnier is named on the bench.
Mark Cornwell starts in the second row alongside Alex Brown, and Peter Buxton starts at blind-side flanker, with captain Jake Boer moving to open-side in place of Hazell.
James Simpson-Daniel makes his return from injury and partners Seti Kiole on the wings. Marcel Garvey misses out due to mumps.
Andy Gomarsall and Henry Paul both returned from England training in the middle of the week and line-up in the Gloucester back line.
Quins have advised supporters without tickets not to travel, as they are not expecting tickets to be available on the day.
15. Jon Goodridge
14. Seti Kiole
13. Terry Fanolua
12. Henry Paul
11. James Simpson-Daniel
10. Duncan McRae
9. Andy Gomarsall
1. Christo Bezuidenhout
2. James Parkes
3. Terry Sigley
4. Mark Cornwell
5. Alex Brown
6. Peter Buxton
7. Jake Boer (c)
8. Adam Balding
Replacements: 16. Noel Curnier
17. Nick Wood
18. Adam Eustace
19. Luke Narraway
20. Alex Page
21. Nathan Mauger
22. Mark Foster
Gloucester travel to Devon to take on the Exeter Chiefs in the opening round of the LV= Cup on Saturday and, with several players away on international duty, Scrum Coach Trevor Woodman feels that the competition provides other players with a great chance to show what they can do.
Man of the Match Matt Kvesic confirmed that Gloucester were anticipating a physical encounter in Oyonnax, and duly got one. The flanker told GRTV that taking the win and denying the home side even a bonus point was a big achievement.
Speaking after he kicked 20 points in Gloucester's 25-15 win over Oyonnax on Saturday evening, Greig Laidlaw admitted that the game had been every bit as challenging as expected and praised the massive effort put in by the pack.
Speaking after the 25-15 European Rugby Challenge Cup win in France, David Humphreys told the local media that he was delighted that his Gloucester team matched Oyonnax's intensity on the night and made it two wins from two in Europe.
Gloucester travel to Oyonnax for the second round of the European Rugby Challenge Cup on Saturday evening, and Director of Rugby David Humphreys is expecting a big test from the French side, feeling that their league position doesn't reflect their recent performances.
Speaking exclusively to Gloucester Rugby TV, Matt Kvesic explained that his decision to extend his contract at Kingsholm was a simple one and that he was hugely excited for the future in Cherry and White.
Speaking after the 55-0 win over CA Brive, Jonny May told GRTV that he's delighted that the team's hard work is starting to pay dividends but was equally happy for his friend and team mate, Charlie Sharples, on what was a big night for his fellow winger.