GARTEH COOPER will start his second Guinness Premiership match of the season at scrum-half when table-topping Gloucester travel to Newcastle on Sunday (3pm).
The Wales number nine comes into the team for Rory Lawson in one of three changes to the side that beat Bourgoin 51-27 at Kingsholm last Saturday.
Marco Bortolami returns to the second row as captain in place of Peter Buxton, who moves to the bench and Alasdair Strokosch starts at number six which means Luke Narraway shifts to the openside in place of Akapusi Qera, who is ruled out with a slight wrist injury.
The rest of Ryan's line-up remains intact for what potentially could be one of the most exciting games of the season between two sides stacked with English talent.
"It is impossible to believe we can operate with the same group of players relentlessly throughout the season because we have been through a very intense period of matches and we are not going to get the best from a guy like Pete Buxton if we simply play and play him," Ryan said.
"We are bringing in an international captain and outstanding player in Marco Bortolami to the second row, Gareth Cooper has looked sharp in his appearances from the bench and Strokosch gives us a work ethic and explosive power we will require.
"Newcastle away from home is one of the most demanding fixtures in the Premiership - they have an outstanding spine to their team and world class players in key areas - it is a hugely important game for both of us.
"I think both teams like to try and play rugby in the right way and that is a great endorsement to both clubs and also the Premiership."
Bortolami's last start was against the Dragons in the EDF Energy Cup at the end of November and he will partner Alex Brown at lock. The front row of Nick Wood, hooker Olivier Azam and tight-head Carlos Nieto remains intact.
Narraway, who has operated at numbers eight and six this season switches to the openside flank, Strokosch comes in at six and Gareth Delve will start his fifth successive game at number eight.
Outside Cooper, Ryan Lamb will wear number 10 and will face Jonny Wilkinson, Anthony Allen and Mike Tindall feature in midfield, while Lesley Vainikolo, the Premiership's leading try scorer with seven; James Simpson-Daniel and Iain Balshaw complete the back three.
The bench is again made into a four-three forward split. Andy Titterrell and Patrice Collazo are the front row replacements and Will James and Buxton the back five options.
Scrum-half Lawson, utility back Willie Walker, who scored against Bourgoin last Saturday and Leon Lloyd complete the three-quarter options.
GLOUCESTER (v Newcastle, Sunday): Iain Balshaw, James Simpson-Daniel, Mike Tindall, Anthony Allen, Lesley Vainikolo; Ryan Lamb, Gareth Cooper; Nick Wood, Olivier Azam, Carlos Nieto, Marco Bortolami (capt), Alex Brown, Alasdair Strokosch, Luke Narraway, Gareth Delve. Reps: Andy Titterrell, Patrice Collazo, Will James, Peter Buxton, Rory Lawson, Willie Walker, Leon Lloyd.
Skipper for the day Aled Thomas praised his Gloucester team mates, especially the younger ones, for the way they took on a tough Ospreys outfit and emerged victorious in the LV= Cup on Saturday afternoon.
Gloucester will field a reshuffled side against the Ospreys in the LV= Cup this weekend, but Backs & Attack Coach Nick Walshe stressed that it's a great opportunity for everyone on duty on Saturday and that maintaining the recent winning run is very important.
Skipper Billy Twelvetrees told GRTV after the win in Brive that the game could have been a tough one to get up for, but that his Gloucester team mates did themselves proud on the night and got a big result.
Reflecting on the 31-20 victory in Brive on Thursday evening, Director of Rugby David Humphreys said that clinching a home European Rugby Challenge Cup quarter-final was the overall aim and duly achieved.
Gloucester Rugby and the Ospreys shared seven tries and 57 points in the LV= Cup at Kingsholm on Saturday. The Cherry and Whites came out on top and the club photographer captured the best of the action.