Last year's winner Chris Ashton will hand his crown over to one of six players and the shortlist includes fellow England international Ugo Monye for his superb try after a great team move in the match against Gloucester on March 26.
The panel opted for Monye's first try of his individual hat-trick and he will be joined by last year's RPA Computacenter Players' Player of the Year Schalk Brits for his effort against Gloucester on April 24.
Welsh fly-half Nicky Robinson also appears on the shortlist for his try against Bath in the West Country derby from the Recreation Ground on October 1 2010.
Other tries on the shortlist include Alesana Tuilagi's third against Gloucester and Bath's South African scrum-half Michael Claassens' try versus Exeter Chiefs as he capitalised on superb work by marauding prop Nathan Catt.
The final try on the shortlist comes from the Aviva Premiership's newcomers Exeter Chiefs in their clash with Northampton Saints on March 6. The try was made in the southern-hemisphere as Nemani Nadolo's offload saw Sireli Naqelevuki scamper across the line as the Chiefs left their opponents for dead.
The Shortlist in Full:
Schalk Brits (Saracens) - Saracens v Gloucester 24th April 2011
Michael Claassens (Bath) - Bath v Exeter 9th April 2011
Ugo Monye (Harlequins) - Harlequins v Gloucester 26th March 2011
Sireli Naqelevuki (Exeter Chiefs) - Exeter v Northampton 6th March 2011
Nicky Robinson (Gloucester) - Bath v Gloucester 1st October 2010
Alesana Tuilagi (Leicester Tigers) - Leicester Tigers v Gloucester 16th April 2011
Voting will open on Sunday May 8 and will close at midnight May 18. Votes can be cast on the RPA website at: www.therpa.co.uk/tryoftheyear
2010 Chris Ashton
2009 David Lemi
2008 Matt Banahan
2007 Tom Varndell
2006 Topsy Ojo
2005 Bruce Reihana
2004 Andy Dunne
2003 Jason Robinson