Luke Narraway and the England Saxons lost their grip on the Churchill Cup on Sunday evening as the trophy headed to Ireland.
The Saxons failed to retain the cup for a third successive year and suffered a six try defeat against a highly charged and physical Ireland A pack.
England scored two second half tries with Ben Woods and Tom Varndell going over, the rest of their points were from the boot of Stephen Myler, scoring three penalties.
Ireland A in contrast ran in two first half tries from Deven Toner and Isaac Boss and four second half tries from Sean Cronin, Felix Jones, Johne Murphy and John Muldoon with Jonathan Sexton adding a penalty, three conversions and a drop goal and Fergus McFadden sharing the kicking duties slotted two further conversions and a penalty.
England Saxons Head Coach Stuart Lancaster said:
"We made some replacements in the second half because in the first we were losing the physical battle."
"Ireland A deserved to win they came at us and were a very though opposition. We have to go away and look at ourselves. At this level there are no second chances. Our desire was there but our execution wasn't."
England Saxons captain Phil Dowson said:
"I'm shell shocked. We took a pasting and there are no excuses. It wasn't a pretty sight at all."
"We just didn't look after our ball whereas in contrast Ireland A did. We didn't work hard enough at the breakdown and we have learned some harsh lessons today."
"We have to go away and look at the videos but we just were not good enough today."
Saxons' built an early 6-0 lead through penalties one for Ireland A being offside and then again minutes later for a knock on.
But, it didn't last long with Sexton slotting an easy three points to make the scores 6-3.
Toner's try for Ireland A came from England being penalised for using feet in the ruck and a five metre scrum saw him power over for them to take a 10-6 lead.
Saxons added a further three points from the boot of Myler to bring them to within a point, 9-10. Another Myler penalty followed which went wide.
In the 25th minute McFadden made a scorching mid-field break which led to Boss eventually finding the line and Sexton added the extras, 9-17.
Myler added another three points on the half hour after Ireland were penalised at the scrum, 12-17.
A double sin binning for fighting in the 33 saw Saxons' Dan Cole and Ireland A's Chris Henry spend some time out.
And a drop goal by Sexton kept Ireland's scoreboard ticking, 12-20.
On the half time buzzer captain Best was sent to the bin for hands in the ruck and Myler failed to slot the three points from the halfway line leaving the scores at 12-20.
Ireland A came back out on the attack and were rewarded, Cronin slipping through England's defence with McFadden adding the conversion to extend their lead to 27-12.
An attacking England lineout led to Woods' try after receiving an outside pass from Stuart Hooper, Myler failed to convert, 17-27.
In the 55th minute Ireland A were fully in their stride and after testing the Saxons defence Jones and Murphy ran over within five minutes of each other.
Jones at close range from a scrum and Murphy from scooping up a Myler cross field kick, to stretch their score to 17-39.
McFadden slotted over another penalty on 65 to add another two points, 17-42.
Ben Woods was sent to the bin for the remainder of the match and John Muldoon powered over in the 74 after a period of camping on England's line and McFadden added the extras, 17-49.
Varndell scored England Saxons' second try in the dying minutes but Shane Geraghty failed to convert to take the final scores to 22-49.
15 Nick Abendanon (Bath Rugby); 14 Tom Varndell (Leicester Tigers), 13 Dominic Waldouck (London Wasps), 12 Brad Barritt (Saracens), 11 Noah Cato (Saracens); 10 Stephen Myler (Northampton Saints), 9 Micky Young (Newcastle Falcons); 1 David Flatman (Bath Rugby), 2 Rob Webber (London Wasps), 3 Dan Cole (Leicester Tigers); 4 Stuart Hooper (Bath Rugby), 5 Nick Kennedy (London Irish); 6 Phil Dowson (Newcastle Falcons, captain), 7 Ben Woods (Leicester Tigers), 8 Luke Narraway (Gloucester Rugby)
16 Joe Ward (London Wasps) rep Webber (70), 17 Tom Mercey (Saracens) rep Cole (56),18 Dean Schofield (Sale Sharks) rep Stuart Hooper (54), 19 Tom Guest (Harlequins) rep Narraway (56), 20 Joe Simpson (London Wasps) rep Young (65), 21 Danny Cipriani (London Wasps) rep Myler (60), 22 Shane Geraghty (London Irish) rep Barritt (60).
Scorers: Tries: Woods, Varndell; Pens: Myler (4).
Sin binned: Cole (33), Woods (73)
15 Felix Jones (Seapoint/Leinster); 14 Denis Hurley (Cork Constitution/Munster), 13 Fergus McFadden (UCD/Leinster), 12 Keith Matthews (Buccaneers/Connacht), 11 Johne Murphy (Leicester); 10 Jonathan Sexton (St.Mary's College/Leinster), 9 Isaac Boss (capt, Ballymena/Ulster); 1 Cian Healy (Clontarf/Leinster), 2 Sean Cronin (Buccaneers/Connacht), 3 Tony Buckley (Shannon/Munster); 4 Donnacha Ryan (Shannon/Munster), 5 Devon Toner (Lansdowne/Leinster); 6 Neil Best (capt, Northampton Saints), 7 Niall Ronan (Shannon/Munster), 8 Chris Henry (Ballymena/Ulster)
16 Dennis Fogarty (Cork Constitution/Munster) rep Cronin (62), 17 Bryan Young (Ballymena/Ulster) rep Healy (75), 18 Trevor Hogan (Blackrock College/Leinster) rep Toner (75), 19 John Muldoon (Buccanneers/Connacht) rep O'Connor (50), 20 Simon Geogh (OId Belvedere/Leinster) rep Boss (75), 21 Niall O'Connor (Belfast Harlequins/Ulster) rep Chris Henry (43), 22 James Downey (Northampton Saints) rep Matthews (75).
Speaking ahead of Saturday's Aviva Premiership fixture at home to Newcastle Falcons (kick off 3pm), Director of Rugby David Humphreys emphasised the importance this weekend of Gloucester building on last week's impressive home victory against the Exeter Chiefs.
Speaking to the assembled national and local media, try-scorer Jonny May was delighted and relieved to have tasted victory on Saturday evening, and is looking forward to the European Rugby Challenge Cup final.
Tom Savage delivered a Man of the Match performance against Exeter Chiefs on his birthday on Saturday evening. He spoke to GRTV after the game about the importance of the European Rugby Challenge Cup win.
Speaking to the local media this week, John Afoa described the hard work that the Cherry and White have been putting in and that he is fighting fit ready for Saturday's European Rugby Challenge Cup semi final clash with Exeter Chiefs.
Gloucester Rugby face Exeter Chiefs this Saturday in the European Rugby Challenge Cup semi-final, and Charlie Sharples, who starts at full back is relishing the challenge of the big Kingsholm occasion.
Gloucester meet the Exeter Chiefs for the fourth time in competitive action this weekend, this time in the semi-final of the European Rugby Challenge Cup. Director of Rugby David Humphreys told the local media this week that this is the sort of game that Gloucester want to be involved in on a regular basis and that he and his team are looking forward to it.
Gloucester Rugby return to Aviva Premiership action against the Newcastle Falcons on Saturday (Kingsholm, kick off 3pm), and make several changes to the side that defeated Exeter Chiefs at home last weekend.