Henry Trinder cut Samoa to pieces as England booked a place in the semi finals of the IRB Toshiba Junior World Championship with their most ruthless display of the season.
The Gloucester centre touched down twice - taking his tally to six tries in six games this season - and created a third for Harlequins wing George Lowe.
Carl Fearns (Sale Sharks) scored twice from the base of the scrum, and Ben Youngs (Leicester Tigers) and Charlie Sharples (Gloucester Rugby) also touched down with London Irish full back Tom Homer adding 14 points and Rory Clegg a second half penalty.
Samoa's slack defending certainly helped them but the way England kept the pressure on their rivals was hugely encouraging and they now face either France or South Africa in next Wednesday's semi final.
England made eight changes to the side that beat Scotland 30-7, the most significant being the return of captain Calum Clark from a month on the sidelines recovering from a knee injury.
They had started slowly against Japan and Scotland but got off to a flier here with two tries from Trinder in the first 10 minutes.
Luke Eves's break and Homer's support run put Trinder away for the first down the right, Homer converting, then Ben Youngs' chip over a ruck into open space saw the ball break away from Winston Wilson in the dead ball area for Trinder to touch down a second.
Homer's 13th and 20th minute penalties established a healthy lead and despite putting themselves under pressure with a few unforced errors England were exposing some striking Samoan weaknesses in defence and at the set piece, despite loosehead Ben Moon giving away 55kg in weight to Uini Atonio.
Samoa missed a glaring chance to get on the board when Rayhan Laulau topped his shot from in front of the posts and England added a third try when Trinder broke and set Lowe scorching to the line.
And any fears about dealing with Samoa's big pack evaporated on the half-hour when they were shoved backwards with Fearns finishing off the pushover try.
They added a fifth try on the stroke of half-time, Fearns breaking and feeding Youngs from the base of a five-metre scrum.
The second half was much more sedate, the job done and the heat and humidity taking their toll with referee Pascal Gauzere stopping play regularly so the players could take on more water.
Clegg added a penalty but England lost some shape after that and Samoa took advantage with a 50th minute try from scrum half Auvasa Falealii.
Fearns added his second on the hour, though, and Sharples jinked over after a neat switch of play by Dave Lewis to take them past the half-century mark 10 minutes from time.
Tom Homer (London Irish; Greig Tonks, Leicester Tigers 41); Charlie Sharples (Gloucester Rugby), Henry Trinder (Gloucester Rugby; Dave Lewis, Gloucester Rugby 54), Luke Eves (Bristol Rugby), George Lowe (Harlequins); Rory Clegg (Newcastle Falcons; Rob Miller, Newcastle Falcons 53), Ben Youngs (Leicester Tigers); Ben Moon (Exeter Chiefs), James Clark (London Irish), Bob Baker (London Wasps), Dan Williams (Gloucester Rugby), Graham Kitchener (Worcester Warriors; James Gaskell, Sale Sharks 55), Courtney Lawes (Northampton Saints), Calum Clark (Leeds Carnegie, captain; Josh Ovens, Bath Rugby 17-23, 59), Carl Fearns (Sale Sharks; Jamie George, Saracens 67).
Speaking to GRTV after the game, Director of Rugby David Humphreys spoke of his delight in securing a 28-6 win over Harlequins at Kingsholm. He hailed the home side's defence which they were quick to turn into attack.
Speaking to the local media, Bill Meakes this week explained how he was relishing the challenge against Harlequins at Kingsholm, and that he is enjoying the opportunity to develop his game time, and repaying the faith from the Cherry and White coaches
Gloucester look to build upon the local derby win over Bath last weekend with Harlequins the visitors to Kingsholm on Saturday (kick off 3pm). Director of Rugby David Humphreys is expecting a close game with the two teams well matched, although it may not be a 78 point thriller like the last time the two teams met.
Named Man of the Match by BT Sport, scrum-half Willi Heinz said after the 15-11 win at Bath on Friday evening that it was a pretty happy Gloucester dressing room and reward for a lot of hard work put in during the week leading up to the game.
Speaking after the 15-11 win over Bath at the Rec on Friday evening, David Humphreys heaped praise on his players, pointing out how they had bounced back after last week's tough defeat to overcome a rough start before controlling the game and earning the win.
Gloucester Rugby hooker Richard Hibbard spoke to the local media this week as the Cherry and Whites prepare to face Bath Rugby in the Aviva Premiership. The Welshman is ready to bounce back at The Rec.
Speaking to the local media about the local derby against Bath at the Rec on Friday evening, Director of Rugby David Humphreys acknowledged that it will be a tough encounter but hugely exciting at the same time and one the squad are looking forward to.
A visibly disappointed Billy Twelvetrees admitted that it was a very sombre Gloucester dressing room as a last minute try and conversion condemned the Cherry and Whites to an 18-19 defeat against Leicester Tigers on Saturday.
After a disappointing opening weekend loss to their Scottish counterparts, England U20s will be eager to bounce back in Italy this evening, with Gloucester flyer Mat Protheroe set to pull the strings from fly half.
Gloucester Rugby make just the one change to the starting line up that won at Bath last Friday evening, flanker Matt Kvesic restored to the starting XV as the Cherry and Whites welcome Harlequins to Kingsholm in the Aviva Premiership on Saturday (kick off 3pm).
The Early Bird deadline for ticket purchases for the Aviva Premiership fixture against Harlequins on Saturday will expire at 6:30pm on Thursday evening, with tickets already limited for one area of Kingsholm.