Dean Mumm will lead his country for the first time, while six others could potentially play their maiden matches at senior level for Australia, after all being named in the Qantas Wallabies side to play Gloucester Rugby tomorrow night.
Mumm, 25, leads a run on combination which will see Brumbies inside centre Tyrone Smith, NSW Waratahs fullback Kurtley Beale, NSW Waratahs lock Dave Dennis and Brumbies tighthead prop Salesi Ma'afu all play their first matches for the Wallabies.
This quartet could be joined in the first timers club by Queensland Reds halfback Richard Kingi and Brumbies flyhalf Matt Toomua, if this year's Australia Under-20 halfback and flyhalf pairing are both called on from the bench during the non-cap match.
Flankers Matt Hodgson, unsighted since being injured in June's season opener against the Barbarians, and Mitchell Chapman, who appeared in then Australian A colours during the 2006 Spring Tour, are also notable inclusions.
The announcement of today's line-up means that all 34 players in the Qantas Wallabies touring party will have received match involvement at the conclusion of the first two matches of the seven-match Spring tour.
And while the Gloucester fixture follows hard on the heels of last weekend's final Bledisloe Cup Test match of the year in Tokyo, the Australian starting XV that will take the field for the midweek tour match still features nine players with Test experience and a combined total of 136 Test caps.
Centre Ryan Cross is the only player required to back up in the run on XV after having started against the All Blacks in Tokyo last weekend.
Qantas Wallabies coach Robbie Deans says this situation was necessitated by the injuries which disrupted the squad in the lead-up to last week's Test match, forcing midfield backs Berrick Barnes and Rob Horne to return home.
"We had intended to avoid backing anyone up in the midweek fixture who had started against the All Blacks, but our injury circumstance in the midfield meant that Ryan was required to start," Deans says.
"We did look at starting Matt Toomua, but as he only joined the squad on Sunday when we arrived in London, and would only have the benefit of one day of preparation with the team, we felt that backing up Ryan was the better option. He got through the game last Saturday well and indicated to me straight after the Test match that he was keen to play."
Five members of the bench from last weekend's Test are included among the run on group, while four of tomorrow night's reserves were also involved in Tokyo.
The Qantas Wallabies team to play Gloucester at the Kingsholm Ground, Gloucester, on 3 November, 7.45pm kick off (6.45am, 4 November, AEST), is:
15. Kurtley Beale (NSW Waratahs)
14. Lachie Turner (NSW Waratahs)
13. Ryan Cross (Western Force)
12. Tyrone Smith (Brumbies)
11. Drew Mitchell (NSW Waratahs)
10. Quade Cooper (Queensland Reds)
9. Luke Burgess (NSW Waratahs)
8. Richard Brown (Western Force)
7. Matt Hodgson (Western Force)
6. Mitchell Chapman (Brumbies)
5. Dean Mumm (NSW Waratahs, captain)
4. Dave Dennis (NSW Waratahs)
3. Salesi Ma'afu (Brumbies)
2. Tatafu Polota Nau (NSW Waratahs)
1. Sekope Kepu (NSW Waratahs)
Run on reserves:
16. Pek Cowan (Western Force)
17. Matt Dunning (Western Force)
18. Mark Chisholm (Brumbies)
19. Wycliff Palu (NSW Waratahs)
20. Richard Kingi (Queensland Reds)
21. Matt Toomua (Brumbies)
22. James O'Connor (Western Force)
Nick Wood captained the Cherry and Whites on Saturday afternoon, and the experienced front rower expressed his pride in the young squad in defeat to Bath on the final day of the Aviva Premiership season.
Lewis Ludlow scored Gloucester's opening try in the 30-50 defeat at Bath on Saturday, part of an impressive performance by the young back row forward. Speaking after the game, he paid tribute to the young Gloucester side who went toe to toe with the Aviva Premiership semi-finalists.
Speaking to the local media after the game, Director of Rugby David Humphreys gave an honest assessment of the game, and expressed his pride in the way his young charges had performed against the title-chasing hosts.
Speaking to the local media this week, Gloucester Rugby scrum half Callum Braley is excited by the challenge of the West Country Derby, and the ex-Bristol man reveals the squad will be giving their all.
Speaking to the local media this week, David Humphreys admitted that team selection for Saturday's Aviva Premiership fixture at Bath has not been an easy one, with numerous players ruled out due to injury and suspension. However, he pledged that whoever is wearing the Cherry and White will be 100% committed to fighting until the very last minute.
Speaking to GRTV after the 35-13 Aviva Premiership victory over London Irish, Tom Savage praised his team mates for sticking to their game plan and showing real character to clinch an impressive win despite only playing with 14 men for nearly an hour.
Speaking to GRTV after the 35-13 win over London Irish at Kingsholm on Saturday, winger Henry Purdy explained that Gloucester keeping their collective composure after being reduced to 14 men was pivotal in clinching the win.
With Connacht Rugby the visitors to Kingsholm on Sunday (kick off 3:30pm) for Sunday's European Rugby Champions Cup play-off, Gloucester ring the changes from the side that took the field against Bath last weekend.
Matt Kvesic was a double winner at the Gloucester Rugby End of Season Awards Dinner on Tuesday, coupled with being named in the England Rugby training squad and the 23-year old is delighted with how his campaign has gone.
Gloucester Rugby held their End of Season Dinner at the Centaur at Cheltenham Racecourse this week. Amongst all the awards, Thinus Delport interviewed James Hook, Laurie Fisher, Charlie Sharples and Billy Twelvetrees.
On Tuesday evening, Gloucester Rugby held the 2015 End of Season Awards Dinner, at The Centaur, Cheltenham Racecourse, and the club photographer was on hand to capture snaps the guests and award winners.