Dean Mumm will lead his country for the first time, while six others could potentially play their maiden matches at senior level for Australia, after all being named in the Qantas Wallabies side to play Gloucester Rugby tomorrow night.
Mumm, 25, leads a run on combination which will see Brumbies inside centre Tyrone Smith, NSW Waratahs fullback Kurtley Beale, NSW Waratahs lock Dave Dennis and Brumbies tighthead prop Salesi Ma'afu all play their first matches for the Wallabies.
This quartet could be joined in the first timers club by Queensland Reds halfback Richard Kingi and Brumbies flyhalf Matt Toomua, if this year's Australia Under-20 halfback and flyhalf pairing are both called on from the bench during the non-cap match.
Flankers Matt Hodgson, unsighted since being injured in June's season opener against the Barbarians, and Mitchell Chapman, who appeared in then Australian A colours during the 2006 Spring Tour, are also notable inclusions.
The announcement of today's line-up means that all 34 players in the Qantas Wallabies touring party will have received match involvement at the conclusion of the first two matches of the seven-match Spring tour.
And while the Gloucester fixture follows hard on the heels of last weekend's final Bledisloe Cup Test match of the year in Tokyo, the Australian starting XV that will take the field for the midweek tour match still features nine players with Test experience and a combined total of 136 Test caps.
Centre Ryan Cross is the only player required to back up in the run on XV after having started against the All Blacks in Tokyo last weekend.
Qantas Wallabies coach Robbie Deans says this situation was necessitated by the injuries which disrupted the squad in the lead-up to last week's Test match, forcing midfield backs Berrick Barnes and Rob Horne to return home.
"We had intended to avoid backing anyone up in the midweek fixture who had started against the All Blacks, but our injury circumstance in the midfield meant that Ryan was required to start," Deans says.
"We did look at starting Matt Toomua, but as he only joined the squad on Sunday when we arrived in London, and would only have the benefit of one day of preparation with the team, we felt that backing up Ryan was the better option. He got through the game last Saturday well and indicated to me straight after the Test match that he was keen to play."
Five members of the bench from last weekend's Test are included among the run on group, while four of tomorrow night's reserves were also involved in Tokyo.
The Qantas Wallabies team to play Gloucester at the Kingsholm Ground, Gloucester, on 3 November, 7.45pm kick off (6.45am, 4 November, AEST), is:
15. Kurtley Beale (NSW Waratahs)
14. Lachie Turner (NSW Waratahs)
13. Ryan Cross (Western Force)
12. Tyrone Smith (Brumbies)
11. Drew Mitchell (NSW Waratahs)
10. Quade Cooper (Queensland Reds)
9. Luke Burgess (NSW Waratahs)
8. Richard Brown (Western Force)
7. Matt Hodgson (Western Force)
6. Mitchell Chapman (Brumbies)
5. Dean Mumm (NSW Waratahs, captain)
4. Dave Dennis (NSW Waratahs)
3. Salesi Ma'afu (Brumbies)
2. Tatafu Polota Nau (NSW Waratahs)
1. Sekope Kepu (NSW Waratahs)
Run on reserves:
16. Pek Cowan (Western Force)
17. Matt Dunning (Western Force)
18. Mark Chisholm (Brumbies)
19. Wycliff Palu (NSW Waratahs)
20. Richard Kingi (Queensland Reds)
21. Matt Toomua (Brumbies)
22. James O'Connor (Western Force)
As Gloucester prepare for their 39th game of the season, against Bordeaux-Begles at Sixways on Sunday, David Humphreys told the local media that this week has been all about getting the players mentally and physically ready after a tough game against Connacht last Sunday.
Speaking to GRTV after the 40-32 victory over Connacht on Sunday, skipper Billy Twelvetrees explained that Gloucester had had to learn to be patient and cut out the errors to earn the win and progress to next weekend's final play-off against Bordeaux-Begles.
Jonny May's superb late score capped a thrilling 40-32 European play-off win over Connacht on Sunday. The winger spoke afterwards of his team's character and spirit as he looked ahead to one more week of rugby.
Speaking to GRTV this afternoon, Director of Rugby David Humphreys hailed the 'never say die' attitude of the team, after despite not being at their best, fighting back to take a 40-32 win after extra time over Connacht.
Jonny May continues on the wing on Sunday as Connacht come to town, and the England wing explains to the local media this week that he is delighted with his form and is looking forward to taking on Pat Lam's men.
Following the recent announcement that XBlades were to become the club's new kit and leisurewear partner, Gloucester Rugby can today (Tuesday 30 June) confirm the opening of a new retail unit, based at Gloucester Quays Outlet Centre, as well as the launch of a brand new online shop.